03500nam 2200613Ia 450 991087751490332120200520144314.01-282-35009-997866123500920-470-77970-50-470-77969-1(CKB)1000000000578365(EBL)406521(OCoLC)476226024(SSID)ssj0000244290(PQKBManifestationID)11188946(PQKBTitleCode)TC0000244290(PQKBWorkID)10169457(PQKB)11131398(MiAaPQ)EBC406521(PPN)19457377X(EXLCZ)99100000000057836520080522d2008 uy 0engur|n|---|||||txtccrThe septins /edited by Peter A. Hall, S.E. Hilary Russell and John R. PringleOxford ;Hoboken, NJ John Wiley-Blackwell20081 online resource (390 p.)Description based upon print version of record.0-470-51969-X Includes bibliographical references and index.The Septins; Contents; Authors and Affiliations; An introduction to the septins; Section I Setting the scene; Chapter 1 Origins and development of the septin field; Chapter 2 Evolution and conserved domains of the septins; Section II Septins in model systems; Chapter 3 Biochemical properties and supramolecular architecture of septin hetero-oligomers and septin filaments; Chapter 4 Yeast septins: a cortical organizer; Chapter 5 Septins in four model fungal systems: diversity in form and function; Chapter 6 Septins in the metazoan model systems Drosophila melanogaster and Caenorhabditis elegansSection III Septins in mammalsChapter 7 The genomics and regulation of the human septin genes; Chapter 8 The functions of septins in mammals; Chapter 9 Septin-interacting proteins in mammals; Chapter 10 Septin functions in the mammalian cytoskeleton; Chapter 11 Septins and the synapse; Chapter 12 Septins and platelets; Chapter 13 Septins and apoptosis; Chapter 14 Septins and human disease; Chapter 15 Insight into septin functions from mouse models; Section IV Envoi; Chapter 16 Septins: 2008 and beyond; Appendix A Septin and septin-like sequences; Appendix B Mammalian septin nomenclatureAppendix C Septin meetings and workshopsIndex; Color Plates""The authors represent most of the key figures and the work and the book as a whole is an essential reference for the newcomer or specialist in this area and for any student of eukaryotic cell structure and function. This is an important and wonderful reference."" -Microbiology Today, May 2009 Septins are an evolutionarily conserved group of GTP-binding and filament-forming proteins that were originally discovered in yeast. Once the preserve of a small band of yeast biologists, the field has grown rapidly in the past few years and now encompasses the whole of animal and funSeptinsProteinsSeptins.Proteins.571.84572.6Hall Peter1936-1996.1751629Russell S. E. Hilary1751630Pringle John R.1943-1751631MiAaPQMiAaPQMiAaPQBOOK9910877514903321The septins4186634UNINA