05356nam 2200625Ia 450 991087729580332120200520144314.01-281-32163-X97866113216350-470-76009-50-470-75982-8(CKB)1000000000405962(EBL)351254(OCoLC)815644680(SSID)ssj0000194696(PQKBManifestationID)11157014(PQKBTitleCode)TC0000194696(PQKBWorkID)10232918(PQKB)10853870(MiAaPQ)EBC351254(EXLCZ)99100000000040596219990607d2000 uy 0engur|n|---|||||rdacontentrdamediardacarrierLower genital tract precancer colposcopy, pathology and treatment /Albert Singer, John M. Monaghan ; assistant author, Swee Chong Quek ; contributing author Alastair R.S. Deery2nd ed.Oxford ;Malden, MA Blackwell Science20001 online resource (341 p.)Description based upon print version of record.0-632-04769-0 Includes bibliographical references and index.Lower Genital Tract Precancer; Contents; Preface to the Second Edition; Preface to the First Edition; Acknowledgements; 1 The Histopathology of Lower Genital Tract Neoplasia; 1.1 Introduction; 1.2 Terminology; The concept of cervical cancer precursors; Biology and natural history; Rationalization of histologic terminology; 1.3 Histopathological features of CIN or SIL; Low-grade disease (mild dysplasia, CIN 1, HPV-CIN 1, LSIL); High-grade disease (moderate or severe dysplasia, CIS, CIN 2 or 3, HSIL); 1.4 Cervical glandular intraepithelial neoplasia and adenocarcinoma-in-situCervical glandular intraepithelial neoplasiaHistologic criteria for CGIN; 1.5 Early invasive carcinoma (microinvasive carcinoma of the cervix); 1.6 Vaginal intraepithelial neoplasia; Adenosis; Histopathology of vaginal intraepithelial neoplasia; 1.7 Vulval precancer; Vulval intraepithelial neoplasia; Paget's disease; 1.8 Related topics; 1.9 References and bibliography; 2 Human Papillomaviruses in Pathogenesis of Lower Genital Tract Neoplasia; 2.1 Introduction; 2.2 Characteristics of human papillomavimses; 2.3 Manifestations of genital HPV infectionsClinical infections (predominately condylomata)Subclinical HPV infections; Latent HPV infections; 2.4 Prevalence of genital HPV infections; Incidence rates of HPV infections; 2.5 Transmission of genital HPV infections; Sexual transmission; Vertical transmission; 2.6 Risk factors for genital HPV infections; 2.7 HPV and cancer precursors; 2.8 HPV infections and the risk for cervical cancer; Case reports and case series; Cohort studies; 2.9 Natural history; Natural history of cervical HPV infections; CIN and HPV have an identical natural history; 2.10 Molecular pathways of HPV oncogenesisThe normal cell cycleThe effect of HPV/host cell interaction-a prerequisite for neoplasia; 2.11 The role of oncogenic HPV detection in the prevention of lower genital tract precancer; As an adjunct to cytology in primary screening; As an adjunct to colposcopy in the management of women presenting with mild or borderline dyskaryosis (ASCUS/AGUS); 2.12 HPV type and type variant as determinants of the natural history; 2.13 References and bibliography; 3 Examination for Cervical Precancer-Use of colposcopy; 3.1 Introduction; 3.2 Tissue basis for colposcopy; The role of the epitheliumThe role of the stromaThe role of the surface configuration; 3.3 The colposcopic examination; The colposcope; The examination; Decontamination of colposcopy clinic equipment; 3.4 New developments in colposcopy; Video colposcopy, image management and electronic databases; 3.5 References and bibliography; 4 Colposcopy of the Normal Cervix -A prerequisite to establish the diagnosis of cervical cancer; 4.1 Introduction; 4.2 Cervical epithelium: natural history; 4.3 Cervical epithelium: topography; 4.4 Cervical epithelium: colposcopic appearances; Original columnar epitheliumOriginal squamous epitheliumThe new Second Edition of Lower Genital Tract Precancer has been extensively revised and expanded to provide a definitive and contemporary reference on this subject. Providing a comprehensive examination of the applications and benefits of modern diagnostic and therapeutic practices in managing lesions of the female lower genital tract, the book is presented in a clear, easy-to-read style and is extensively illustrated. The text covers investigative procedures and techniques, reviews the normal and abnormal cervix and fully appraises the diagnosis and management of both benign and maligGenerative organs, FemalePrecancerous conditionsCancerGenerative organs, FemalePrecancerous conditions.Cancer.616.99/466Singer Albert903337Monaghan John M925979MiAaPQMiAaPQMiAaPQBOOK9910877295803321Lower genital tract precancer2078989UNINA