05178nam 2200613Ia 450 991087669850332120200520144314.01-280-21343-497866102134360-470-79017-20-470-77457-61-4051-4810-1(CKB)1000000000351677(EBL)238471(OCoLC)475948896(SSID)ssj0000268184(PQKBManifestationID)11218103(PQKBTitleCode)TC0000268184(PQKBWorkID)10235407(PQKB)11238591(MiAaPQ)EBC238471(EXLCZ)99100000000035167720020805d2004 uy 0engur|n|---|||||rdacontentrdamediardacarrierVitamins their role in the human body /G.F.M. BallOxford Blackwell Science20041 online resource (450 p.)Description based upon print version of record.0-632-06478-1 Includes bibliographical references and index.Contents; 8.7 Immunoregulatory properties; 8.11 Toxicity; Further reading; Foreword; Preface; 1 Historical Events Leading to the Establishment of Vitamins; 1.1 Introduction; 1.2 Early studies of nutritionally related diseases; 1.3 Experiments on formulated diets; 1.4 Naming of the vitamins; Further reading; References; 2 Nutritional Aspects of Vitamins; 2.1 Definition and classification of vitamins; 2.2 Nutritional vitamin deficiency; 2.3 Stability and bioavailability of vitamins; 2.4 Vitamin requirements; Further reading; References; 3 Background Physiology and Functional Anatomy3.1 Movement of solutes across cell membranes and epithelia3.2 The blood-brain, blood-cerebrospinal fluid and placental barriers; 3.3 Functional anatomy of the small and large intestine, liver and kidney; 3.4 Digestion and absorption; 3.5 Glucose transport; 3.6 Digestion, absorption and transport of dietary fat; 3.7 Neural and endocrine communication systems; 3.8 Structure of bone and its growth and development; 3.9 Cell proliferation; Further reading; References; 4 Background Biochemistry; 4.1 Major degradation pathways in which B-group vitamins are involved as coenzymes4.2 Amino acid utilization4.3 Defences against free radicals and other reactive species; 4.4 Haemostasis; 4.5 Atherosclerosis; Further reading; References; 5 Background Immunology; 5.1 General features of the immune system; 5.2 Innate immunity; 5.3 Inflammation; 5.4 Acquired immunity; 5.5 Cytokines; 5.6 Hypersensitivity; 5.7 Immune suppression; 5.8 Neuroendocrine modulation of immune responses; Further reading; References; 6 The Genetic Control of Protein Synthesis and its Regulation by Nuclear Hormone Receptors; 6.1 Functional structure of DNA; 6.2 Role of RNA in protein synthesis6.3 Gene expression6.4 Mutation and polymorphism; 6.5 Basal transcription; 6.6 Regulated transcription; 6.7 Jun, Fos and the AP-1 complex; 6.8 Nuclear hormone receptors as regulators of protein synthesis; Further reading; References; 7 Vitamin A: Retinoids and Carotenoids; 7.1 Historical overview; 7.2 Chemistry and biological functions; 7.3 Dietary sources; 7.4 Absorption, transport and metabolism; 7.5 Nutritional factors that influence vitamin A status; 7.6 The role of vitamin A in vision; 7.7 Retinoids as regulators of gene expression; 7.8 Effects of vitamin A on the immune system7.9 Role of vitamin A in bone metabolism and embryonic development7.10 Vitamin A and cancer; 7.11 Vitamin A deficiency and toxicity; Further reading; References; 8 Vitamin D; 8.1 Historical overview; 8.2 Chemistry and biological functions; 8.3 Dietary sources; 8.4 Cutaneous synthesis, intestinal absorption, transport and metabolism; 8.5 Molecular action of the vitamin D hormones; 8.6 Calcium and phosphate homeostasis; 8.8 Effects of vitamin D on insulin secretion; 8.9 Vitamin D-related diseases; 8.10 Therapeutic applications of vitamin D analogues; 8.12 Dietary requirement; Further readingReferencesThis single-source reference draws together the current knowledge of the vitamins' biological properties in the context of human nutrition. Vitamins are co-enzymes, antioxidants or precursors of hormones and are therefore involved in a great many biochemical and physiological processes. They play a vital role in the maintenance of health, and there is evidence that dietary sources of vitamins have beneficial effects in the prevention of heart-related diseases, bone diseases and possibly cancer.Following introductory chapters on historical and nutritional aspects of vitamins, thVitaminsPhysiological effectVitamins in human nutritionVitaminsPhysiological effect.Vitamins in human nutrition.613.286Ball G. F. M969189MiAaPQMiAaPQMiAaPQBOOK9910876698503321Vitamins2202104UNINA