03861nam 22006495 450 991087219770332120240705125446.09789819705115(electronic bk.)978981970510810.1007/978-981-97-0511-5(MiAaPQ)EBC31518804(Au-PeEL)EBL31518804(CKB)32674598800041(DE-He213)978-981-97-0511-5(EXLCZ)993267459880004120240705d2024 u| 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierNon B cell-Derived Immunoglobulins The Structure, Characteristics and the Implication on Clinical Medicine /edited by Xiaoyan Qiu, Jing Huang, Xiaojun Xu1st ed. 2024.Singapore :Springer Nature Singapore :Imprint: Springer,2024.1 online resource (193 pages)Advances in Experimental Medicine and Biology,2214-8019 ;1445Print version: Qiu, Xiaoyan Non B Cell-Derived Immunoglobulins Singapore : Springer Singapore Pte. Limited,c2024 9789819705108 Includes bibliographical references.Chapter 1 The history of appreciation of immunoglobulin and the discovery of non-B cell derived immunoglobulins -- Chapter 2 Expression profile of non B-Ig in different lineage cells -- Chapter 3 Unique V(D)J recombination characteristics and repertoire of non B-Ig -- Chapter 4 Unique regulation mechanismof non B-Ig gene -- Chapter 5 Unique structure and function of non B-Ig -- Chapter 6 Comparison of non B-Ig and B-Ig -- Chapter 7 Functionsand clinical relevanceof non-B cell derived immunoglobulin in liver -- Chapter 8 Significance of non-Bcell derived immunoglobulins in renal disease -- Chapter 9 Functions and clinical significance of myocardial cell-derived Immunoglobulins -- Chapter 10 Biological functions and clinical significance of intestinal non B-Immunoglobulins -- Chapter 11 Function of IgG and IgA in normal human skin -- Chapter 12 Significance of cancer-derived IgG in lung cancer -- Chapter 13 Significance of cancer-derived IgG in breast cancer -- Chapter 14 Significance of cancer-derived IgG in pancreatic cancer -- Chapter 15 Biological functions and clinical significance of non B-Ig in hemopoietic system.This book has expanded classic concept of immunology. Immunoglobulins have been widely discovered to be produced by many non-B cells. The non B cell-derived Igs display multifunction, which not only includes antibody activities and cellular biological functions under physiological conditions, but also directly participate in the pathological process of malignant tumour and immune-related diseases. This book provides new perspectives and a solid foundation for medical students, basic and clinical scientists to re-understand and broaden the physiological and pathological significance of Ig.Advances in Experimental Medicine and Biology,2214-8019 ;1445ImmunologyMedicineResearchBiologyResearchLife sciencesImmunologyBiomedical ResearchLife SciencesBiomedical ResearchImmunology.MedicineResearch.BiologyResearch.Life sciences.Immunology.Biomedical Research.Life Sciences.Biomedical Research.616.0798Qiu XiaoyanHuang JingXu XiaojunMiAaPQMiAaPQMiAaPQ9910872197703321Non B cell-Derived Immunoglobulins4238649UNINA