03118nam 22005535 450 991084758720332120240409125106.03-031-41777-110.1007/978-3-031-41777-1(CKB)31403846400041(MiAaPQ)EBC31267321(Au-PeEL)EBL31267321(DE-He213)978-3-031-41777-1(EXLCZ)993140384640004120240409d2024 u| 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierStroke Genetics[electronic resource] /edited by Pankaj Sharma, James F. Meschia3rd ed. 2024.Cham :Springer International Publishing :Imprint: Springer,2024.1 online resource (626 pages)3-031-41776-3 Introduction -- Familial stroke epidemiology -- Association study results -- GWAS -- Aneurysms/carvernous/AVM -- ICH/amyloid/microbleeds -- CADASIL -- Fabry -- MELAS -- Sickle -- Other monogenic -- White matter disease -- Carotid atherosclerosis -- Dissection -- Pharmacogenomics -- Non-Caucasian stroke genetics -- Small vessel disease -- Genetics of neuroimaging in stroke -- Cerebrovenous thrombosis -- Ethics.This revised, expanded third edition updates the reader on this fast moving field as well providing an overall understanding of the genetics of complex diseases by using stroke as a paradigm. The reader will gain a comprehensive understanding of cerebrovascular genetics including the epidemiological evidence for the genetic basis of ischemic and hemorrhagic stroke, knowledge of its molecular basis from association, linkage and recent genome-wide studies, and also monogenic disorders. Finally, the legal and ethical complexities in dealing with these issues are discussed. Stroke Genetics is a valuable resource for neurologists, stroke physicians, hypertension specialists, internists, clinical pharmacologists and those in training, as well as researchers in the field of disease genetics. Each chapter now contains teaching/training MCQs to help with retention of information learnt from each chapter and this will be of considerable use to those training or about to the examined in the field of inherited stroke. Additional questions via app: Download the Springer Nature Flashcards app for free and use exclusive additional material to test your knowledge.NeurologyInternal medicineMedical geneticsNeurologyInternal MedicineMedical GeneticsNeurology.Internal medicine.Medical genetics.Neurology.Internal Medicine.Medical Genetics.616.81042Sharma Pankaj769368Meschia James F1643698MiAaPQMiAaPQMiAaPQBOOK9910847587203321Stroke Genetics4156210UNINA