03418nam 2200613Ia 450 991084171370332120230331005421.01-282-34760-897866123476030-470-51377-20-470-51378-0(CKB)1000000000377201(EBL)470474(OCoLC)609849386(SSID)ssj0000290049(PQKBManifestationID)11211084(PQKBTitleCode)TC0000290049(PQKBWorkID)10404397(PQKB)11245463(MiAaPQ)EBC470474(EXLCZ)99100000000037720119890126d1989 uy 0engur|n|---|||||txtccrThe Biology of hyaluronan[electronic resource] /[editors: David Evered and Julie Whelan.]Chichester, UK ;New York Wiley19891 online resource (312 p.)Ciba Foundation symposium ;143Based on a "Symposium on the Biology of Hyaluronan, held at the Ciba Foundation, London, 27-29 September 1988."0-471-92305-2 Includes bibliographies and index.THE BIOLOGY OF HYALURONAN; Contents; Participants; Introduction; Secondary structures in hyaluronan solutions: chemical and biological implications; Identification and regulation of the eu karyotic hyaluronate synthase; Turnover and metabolism of hyaluronan; Enzymic pathways of h yal u ronan catabolism; The interaction of hyaluronate with the cell surface: the hyalu ronate receptor and the core protein; H yaluronan and hyalu ronan- binding proteins in cartilaginous tissues; The role of a cell-associated hyaluronan- binding protein in fibroblast behaviourHyaluronate-cell interactions and growth factor regulation of hyaluronate synthesis during limb developmentThe role and tu rnou r-assoc regulation of ated hyaluronan; Interactions between cells of the immune system and hyaluronate synthesis by human dermal fibroblasts; Hyaluronan and angiogenesis; Hyaluronan and hyaluronectin in the nervous system; Changes in hyaluronan concentration in tissues and body fluids in disease states; The specific interaction between fibrin(ogen) and hyaluronan: possible consequences in haemostasis, inflammation and wound he; Clinical uses of hyaluronanGeneral discussionsumming-UP; Index of contributors; Subject indexPresents state-of-the-art applications in hyaluronan research, from hyaluronan's physicochemical properties to its clinical role as a connective tissue marker and its surgical implications, particularly in ear, eye and orthopaedic surgery. Covers hyaluronan's synthesis and catabolism, its role in cells, its interactions with specific binding proteins, and its role in the embryonic nervous system.Ciba Foundation symposium ;143.Hyaluronic acidPhysiological effectPhysiologyHyaluronic acidPhysiological effect.Physiology.591.19254616.994071Evered David857127Whelan Julie322651MiAaPQMiAaPQMiAaPQBOOK9910841713703321The Biology of hyaluronan4144871UNINA