05711nam 2200721Ia 450 991083116090332120230721005132.01-282-11320-897866121132080-470-43492-91-61583-174-60-470-43491-0(CKB)1000000000719448(EBL)427578(OCoLC)437111240(SSID)ssj0000207868(PQKBManifestationID)11954585(PQKBTitleCode)TC0000207868(PQKBWorkID)10237098(PQKB)10349844(MiAaPQ)EBC427578(EXLCZ)99100000000071944820080726d2009 uy 0engur|n|---|||||txtccrNanochromatography and nanocapillary electrophoresis[electronic resource] pharmaceutical and environmental analyses /Imran Ali, Hassan Y. Aboul-Enein, Vinod K. GuptaHoboken, N.J. John Wiley & Sonsc20091 online resource (288 p.)Description based upon print version of record.0-470-17851-5 Includes bibliographical references and index.NANOCHROMATOGRAPHY AND NANOCAPILLARY ELECTROPHORESIS; CONTENTS; PREFACE; ACKNOWLEDGMENTS; 1 Introduction; 1.1. Nanoanalyses; 1.2. Definition of Nanochromatography and Nanocapillary Electrophoresis; 1.3. Nanochromatography and Nanocapillary Electrophoresis; 1.4. Fabrication of Microdevices; 1.5. Developments in Nanoanalyses; 1.6. Data Integration; 1.7. Protocol of Nanoanalyses; 1.8. Scope of the Book; 1.9. Conclusion; References; 2 Fabrication of Microchips; 2.1. Introduction; 2.2. Substrates; 2.3. Techniques of Fabrication; 2.3.1. Glass Chips; 2.3.2. Quartz Chips; 2.3.3. Silica Chips2.3.4. Polymer Chips2.3.5. Plastic Chips; 2.3.6. Chips and the Polymerase Chain Reaction; 2.4. Surface Modification; 2.4.1. Modification by Polymers; 2.4.2. Modification by Silica Gel; 2.4.3. Modification by Monolithics; 2.4.4. Modification by Sulfonation; 2.5. Designs of Chips; 2.6. Bindings in Chips; 2.7. Conclusion; References; 3 Instrumentation of Nanochromatography and Nanocapillary Electrophoresis; 3.1. Introduction; 3.2. Nanoliquid Chromatography (NLC); 3.2.1. Mobile Phase Reservoirs; 3.2.2. Mobile Phases and Flow Calibration; 3.2.3. Mobile Phase Tubings; 3.2.4. Solvent Delivery Pump3.2.5. Sample Injector3.2.6. Separation Chips; 3.2.7. Detectors; 3.2.8. Recorder; 3.2.9. Sample Preparation Units; 3.3. Nanocapillary Electrophoresis; 3.3.1. Separation Chip; 3.3.2. Background Electrolyte and Its Reservoirs; 3.3.3. Sample Injection Port; 3.3.4. Detectors; 3.3.5. Recorder; 3.3.6. Sample Preparation Units; 3.4. Conclusion; References; 4 Detection in Nanochromatography and Nanocapillary Electrophoresis; 4.1. Introduction; 4.2. Mass Spectrometer Detectors; 4.3. Fluorescence Detectors; 4.4. Electrochemical Detectors; 4.5. Element Specific Detectors; 4.6. Miscellaneous Detectors4.7. ConclusionReferences; 5 Sample Preparation in Nanochromatography and Nanocapillary Electrophoresis; 5.1. Introduction; 5.2. Sample Preparation; 5.3. Sampling; 5.3.1. Biological Samples; 5.3.1.1. Blood; 5.3.1.2. Urine; 5.3.1.3. Tissues; 5.3.1.4. Plants; 5.3.1.5. Food Stuffs; 5.3.2. Environmental Samples; 5.3.2.1. Air; 5.3.2.2. Water; 5.3.2.3. Sediment and Soils; 5.4. Preservation; 5.5. Filtration; 5.6. Digestion/Homogenization; 5.7. Extractions; 5.8. Clean Up; 5.9. Preconcentration; 5.10. Off-Line Nanosample Preparation Methods; 5.10.1. Nano Solid Phase Extractions5.10.2. Nano Membrane Extractions5.10.3. Nano Miscellaneous Extractions; 5.11. Online Nanosample Preparation Methods; 5.12. Conclusion; References; 6 Nano-High Performance Liquid Chromatography; 6.1. Introduction; 6.2. Nano-HPLC; 6.3. Applications; 6.3.1. Nano-HPLC of Biological Matrices; 6.3.1.1. Proteomics; 6.3.1.2. Drugs Development and Design; 6.3.1.3. Environmental Analysis; 6.4. Optimization of Separations in Nano-HPLC; 6.5. Troubleshooting in Nano-HPLC; 6.6. Conclusion; References; 7 Nanocapillary Electrochromatography and Nanomicellar Electrokinetic Chromatography; 7.1. Introduction7.2. Nanocapillary ElectrochromatographyDetection of drugs at low concentration is required in a variety of biological and medical situations, in order to avoid harmful side effects posed by some drug residues. The book details the instrumentation, detection, and application of nano chromatography (that is, any chromatographic and capillary electrophoretic method dealing with the detection of a sample at nano gram per liter or lower) and capillary electrophoresis in the analyses of biological and environmental samples. Methods discussed include: Nano Gas Chromatography, Nano Capillary Electrophoresis, Nano Chiral Chromatography, MicChromatographic analysisCapillary electrophoresisDrugsAnalysisPollutantsAnalysisNanoparticlesAnalysisChromatographic analysis.Capillary electrophoresis.DrugsAnalysis.PollutantsAnalysis.NanoparticlesAnalysis.543.8543/.8Ali Imran1345554Aboul-Enein Hassan Y98954Gupta Vinod K.1953-1638984MiAaPQMiAaPQMiAaPQBOOK9910831160903321Nanochromatography and nanocapillary electrophoresis3981702UNINA