03215oam 2200733zu 450 991083080830332120230607213101.00-470-84654-297866105554441-280-55544-0(CKB)111056485557304(SSID)ssj0000147114(PQKBManifestationID)11151097(PQKBTitleCode)TC0000147114(PQKBWorkID)10016003(PQKB)10127026(MiAaPQ)EBC4957428(Au-PeEL)EBL4957428(CaONFJC)MIL55544(OCoLC)53847682(EXLCZ)9911105648555730420160829d2002 uy engurcnu||||||||txtccrEndocrine facets of ageing[Place of publication not identified]John Wiley & Sons20021 online resource (298 pages)Novartis Foundation Symposia ;v.Vol. 242Bibliographic Level Mode of Issuance: Monograph0-471-48636-1 0-470-85188-0 Social and medical developments have recently led to a dramatic increase in life expectancy. This has inspired the study of organismic changes associated with healthy ageing, in particular the erosion of homeostatic capabilities in multiple endocrine systems. This book reviews advances in the understanding of endocrine facets of ageing. It considers the relative magnitudes and time courses of different endocrine adaptations in the ageing human and experimental animal, addressing the influence of external factors on the rates of progression of endocrine sequelae in ageing, the mechanisms that underlie the disarray of endocrine axes in ageing, and the implications of therapeutic reconstitution of hormones in ageing. This book: considers the mechanisms of ageing and hormonal changes that occur with age; discusses healthy ageing and the relationships between hormonal changes and pathophysiological conditions such as atherosclerosis and age-related bone loss; and draws together contributions from basic and clinical research, to identify and stimulate promising new research directions.Novartis Foundation SymposiaAnatomyGrowth and DevelopmentPhysiological ProcessesPhysiological PhenomenaPhenomena and ProcessesAgingEndocrine SystemHuman Anatomy & PhysiologyHILCCHealth & Biological SciencesHILCCPhysiologyHILCCAnatomyGrowth and DevelopmentPhysiological ProcessesPhysiological PhenomenaPhenomena and ProcessesAgingEndocrine SystemHuman Anatomy & PhysiologyHealth & Biological SciencesPhysiology612.67Chadwick DerekGoode JamiePQKBBOOK9910830808303321Endocrine facets of ageing3972660UNINA