03857nam 2200673Ia 450 991083075280332120230721022551.01-282-28012-097866122801220-470-43798-70-470-43797-9(CKB)1000000000789578(EBL)455922(OCoLC)466446801(SSID)ssj0000354813(PQKBManifestationID)11258216(PQKBTitleCode)TC0000354813(PQKBWorkID)10314583(PQKB)10641838(MiAaPQ)EBC455922(EXLCZ)99100000000078957820080624d2009 uy 0engur|n|---|||||txtccrSystems biology and synthetic biology[electronic resource] /edited by Pengcheng Fu, Sven PankeHoboken, N.J. John Wiley & Sonsc20091 online resource (674 p.)Description based upon print version of record.0-471-76778-6 Includes bibliographical references and index.SYSTEMS BIOLOGY AND SYNTHETIC BIOLOGY; CONTENTS; Foreword; Contributors; 1 Introduction; 2 Basics of Molecular Biology, Genetic Engineering, and Metabolic Engineering; 3 High-Throughput Technologies and Functional Genomics; 4 Genomic Signal Processing of DNA Microarray Data for the Enhanced Prediction of Axillary Lymph Node Status of Breast Cancer Tumors; 5 Recombinant Genomes: Novel Resources for Systems Biology and Synthetic Biology; 6 In silico Genome-Scale Metabolic Models: The Constraint-Based Approach and its Applications7 Mathematical Modeling of Genetic Regulatory Networks: Stress Responses in Escherichia coli8 Synthetic Life: Ethobricks for a New Biology; 9 Yeast as a Prototype for Systems Biology; 10 Construction and Applications of Genome-Scale in silico Metabolic Models for Strain Improvement; 11 Synthetic Biology: Putting Engineering into Bioengineering; 12 Rationales of Gene Design and de novo Gene Construction; 13 Self-Replication in Chemistry and Biology; 14 The Synthetic Approach for Regulatory and Metabolic Circuits; 15 Synthetic Gene Networks16 The Theory of Biological Robustness and its Implication to Cancer17 Nucleic Acid Engineering; 18 Potential Applications of Synthetic Biology in Marine Microbial Functional Ecology and Biotechnology; 19 On Fundamental Implications of Systems and Synthetic Biology; 20 Outstanding Issues in Systems and Synthetic Biology; IndexThe genomic revolution has opened up systematic investigations and engineering designs for various life forms. Systems biology and synthetic biology are emerging as two complementary approaches, which embody the breakthrough in biology and invite application of engineering principles. Systems Biology and Synthetic Biology emphasizes the similarity between biology and engineering at the system level, which is important for applying systems and engineering theories to biology problems. This book demonstrates to students, researchers, and industry that systems biology relies on synthetic biology BiotechnologyGenetic engineeringBiological systemsBiotechnology.Genetic engineering.Biological systems.572.838620.8660.6BIO 180fstubCIT 972fstubWD 9200rvkWH 2000rvkFu Pengcheng1689865Panke Sven1689866MiAaPQMiAaPQMiAaPQBOOK9910830752803321Systems biology and synthetic biology4065240UNINA