03942nam 2200673Ia 450 991083069340332120170809164744.01-280-90082-297866109008240-470-31939-90-470-31940-2(CKB)1000000000357042(EBL)297464(SSID)ssj0000259603(PQKBManifestationID)11244615(PQKBTitleCode)TC0000259603(PQKBWorkID)10186298(PQKB)11770170(MiAaPQ)EBC297464(OCoLC)181345961(PPN)250337878(EXLCZ)99100000000035704220061121d2007 uy 0engur|n|---|||||txtccrTinkering[electronic resource] the microevolution of development /[editors: Gregory Bock and Jamie Goode]Chichester ;Hoboken, NJ John Wiley & Sons20071 online resource (301 p.)Novartis Foundation symposium ;284Description based upon print version of record.0-470-03429-7 Includes bibliographical references and indexes.Tinkering: The Microevolution of Development; Contents; The evolutionary developmental biology of tinkering: an introduction to the challenge; Tinkering: a conceptual and historical evaluation; DISCUSSION; Tinkering: new embryos from old-rapidly and cheaply; DISCUSSION; The relationship between development and evolution through heritable variation; DISCUSSION; Genetic networks as transmitting and amplifying devices for natural genetic tinkering; DISCUSSION; Butterfly eyespot patterns and how evolutionary tinkering yields diversity; DISCUSSION; GENERAL DISCUSSION ITinkering with transcription factor proteins: the role of transcription factor adaptation in developmental evolutionDISCUSSION; Tinkering with constraints in the evolution of the vertebrate limb anterior-posterior polarity; DISCUSSION; Affecting tooth morphology and renewal by fine-tuning the signals mediating cell and tissue interactions; DISCUSSION; GENERAL DISCUSSION II; Evolution of covariance in the mammalian skull; DISCUSSION; The developmental genetics of microevolution; DISCUSSION; The economy of tinkering mammalian teeth; DISCUSSIONPelvic skeleton reduction and Pitx1 expression in threespine stickleback populationsDISCUSSION; Using patterns of fin and limb phylogeny to test developmental- evolutionary scenarios; DISCUSSION; Craniofacial variation and developmental divergence in primate and human evolution; DISCUSSION; Contributor Index; Subject IndexMuch recent research in evolutionary developmental biology has focused on the origin of new body plans. However, most evolutionary change at the population and species level consists of tinkering: small-scale alterations in developmental pathways within a single body plan. Such microevolutionary events have been well studied on a population genetic level and from the perspective of adaptive phenotypic evolution, but their developmental mechanisms remain poorly studied. This book explores both theoretical and practical issues of tinkering. It features a wide range of perspectives to addresNovartis Foundation symposium ;284.Molecular biologyMolecular evolutionTinkeringMicroevolutionDevelopmentNovartisMolecular biology.Molecular evolution.572.8Bock Gregory322650Goode Jamie283336Novartis Foundation.MiAaPQMiAaPQMiAaPQBOOK9910830693403321Tinkering3927408UNINA