03077nam 2200637Ia 450 991045465410332120200520144314.01-280-74213-597866107421340-309-54912-4(CKB)1000000000521967(EBL)3564101(SSID)ssj0000279944(PQKBManifestationID)11214222(PQKBTitleCode)TC0000279944(PQKBWorkID)10268500(PQKB)11666348(MiAaPQ)EBC3564101(Au-PeEL)EBL3564101(CaPaEBR)ebr10160712(CaONFJC)MIL74213(OCoLC)929504295(EXLCZ)99100000000052196720050316d2005 uy 0engurcn|||||||||txtccrGlobalization of materials R&D[electronic resource] time for a national strategy /Committee on Globalization of Materials Research and Development, National Materials Advisory Board, Division on Engineering and Physical Sciences, National Research Council of the National AcademiesWashington, D.C. National Academies Pressc20051 online resource (215 p.)Description based upon print version of record.0-309-09603-0 Includes bibliographical references.""Front Matter""; ""Preface""; ""Acknowledgment of Reviewers""; ""Contents""; ""Executive Summary""; ""1 Materials as Global Activity: Setting the Scene""; ""2 Indicators for Trends in Globalization""; ""3 Benchmarking of Materials Science and Engineering R&D""; ""4 The Regulatory Regime as a Driver""; ""5 Assessing the Impacts of Materials Science and Engineering R&D Globalization""; ""6 Conclusions and Recommendations""; ""Appendixes""; ""A Committee Biographies""; ""B Presentations to the Committee at its Public Meetings""; ""C Global Trends in MSE Patents""""D Global Trends in Literature Authorship""""E Results of the Community Poll""; ""F Superalloy Case Study""; ""G Environmental and Safety and Health Regulations""; ""H Defining 21st Century Defense Needs""GlobalizationEconomic aspectsUnited StatesGlobalizationPolitical aspectsUnited StatesMaterials scienceGovernment policyUnited StatesMaterials scienceResearchElectronic books.GlobalizationEconomic aspectsGlobalizationPolitical aspectsMaterials scienceGovernment policyMaterials scienceResearch.620.1122National Research Council (U.S.).Committee on Globalization of Materials Research and Development.National Research Council (U.S.).National Materials Advisory Board.MiAaPQMiAaPQMiAaPQBOOK9910454654103321Globalization of materials R&D2148972UNINA05113nam 2200601 a 450 991083065480332120220609161331.01-280-52047-797866105204733-527-60538-X3-527-60188-0(CKB)1000000000019365(EBL)482328(OCoLC)68919709(SSID)ssj0000204267(PQKBManifestationID)11181348(PQKBTitleCode)TC0000204267(PQKBWorkID)10196084(PQKB)10443914(MiAaPQ)EBC482328(PPN)243300557(EXLCZ)99100000000001936520040608d2004 uy 0engur|n|---|||||txtccrModern carbonyl olefination[electronic resource] /Takeshi Takeda (ed.)Weinheim Wiley-VCHc20041 online resource (367 p.)Description based upon print version of record.3-527-30634-X Includes bibliographical references and index.Modern Carbonyl Olefination; Contents; Preface; List of Authors; 1 The Wittig Reaction; 1.1 Introduction; 1.2 The ""Classic"" Wittig Reaction; 1.2.1 Mechanism and Stereoselectivity; 1.2.2 Nature of the Ylide and Carbonyl Compound; 1.2.3 Reagents and Reaction Conditions; 1.3 Horner-Wadsworth-Emmons Reaction; 1.3.1 Mechanism and Stereochemistry; 1.3.2 Reagents and Reaction Conditions; 1.4 Horner-Wittig (HW) Reaction; 1.4.1 Mechanism and Stereochemistry; 1.4.2 Reagents and Reaction Conditions; 1.5 Conclusion; References; 2 The Peterson and Related Reactions; 2.1 Introduction2.2 Stereochemistry and the Reaction Mechanism of the Peterson Reaction2.2.1 Stereochemistry and the Reaction Mechanism of the Peterson Reaction of β-Hydroxyalkylsilanes; 2.2.1.1 Stepwise Mechanism; 2.2.1.2 Reaction Mechanism via a 1,2-Oxasiletanide; 2.2.2 Reaction Mechanism of the Addition Step of an α-Silyl Carbanion to a Carbonyl Compound; 2.2.2.1 Approach Control of the Transition State; 2.2.2.2 Concerted Mechanism; 2.2.2.3 Chelation Control Mechanism; 2.2.3 Theoretical Calculations on the Reaction Mechanism; 2.2.4 Convergently Stereoselective Peterson Reactions2.3 Generation of α-Silyl Carbanions and their Peterson Reactions2.3.1 Generation of α-Silyl Carbanions from α-Silylalkyl Halides; 2.3.1.1 Generation of α-Silyl Grignard Reagents from α-Silylalkyl Halides; 2.3.1.2 Generation of α-Silyl Alkyllithium Reagents from α-Silylalkyl Halides; 2.3.1.3 Synthesis of Terminal Alkenes by the Use of α-Silyl Carbanions Generated from α-Silylalkyl Halides; 2.3.1.4 Reactions of α-Silyl Carbanions Generated from α-Silylalkyl Halides with Esters, Carboxylic Acids, and Acetals; 2.3.1.5 The Reformatsky-Peterson Reactions of α-Silylalkyl Halides2.3.2 Generation of α-Silyl Carbanions by Deprotonation of Alkylsilanes2.3.2.1 Generation of α-Silyl Carbanions Bearing an Aryl or a Heteroaryl Group; 2.3.2.2 Generation of α-Silyl Carbanions Bearing an Alkoxy Group; 2.3.2.3 Generation of α-Silyl Carbanions Bearing a Nitrogen-Containing Group; 2.3.2.4 Generation of α-Silyl Carbanions Bearing a Sulfur-Containing Group; 2.3.2.5 Generation of α-Silyl Carbanions Bearing a Phosphorus-Containing Group; 2.3.2.6 Generation of α-Silyl Carbanions Bearing a Halogen Group; 2.3.2.7 Generation of α-Silyl Carbanions from α-Silyl Ketones2.3.2.8 Generation of α-Silyl Carbanions Bearing an Ester Group2.3.2.9 Generation of α-Silyl Carbanions Bearing a Lactone Group; 2.3.2.10 Generation of α-Silyl Carbanions Bearing Thiocarboxylate or Dithiocarboxylate Ester Groups; 2.3.2.11 Generation of α-Silyl Carbanions Bearing an Imino Group; 2.3.2.12 Generation of α-Silyl Carbanions Bearing an Amide Group; 2.3.2.13 Generation of α-Silyl Carbanions Bearing a Cyano Group; 2.3.2.14 Generation of α-Silyl Carbanions from Allylsilanes; 2.3.2.15 Generation of α-Silyl Carbanions from Propargylsilanes2.3.3 Generation of α-Silyl Carbanions by Substitution of a HeteroatomWhile this important reaction class is among the most important and most widely used in organic chemistry, this is the first book to summarize the many different olefination methods, including:* Wittig reaction* Peterson reaction* Julia olefination * Utilizing the Tebbe and related reagents* Low-valent chromium, zinc or titanium mediated olefination* McMurry coupling plus the related reactions in each case and the application to asymmetric synthesis. It thus collates in one ready reference the current level of knowledge as well as new developments in this constantlyCarbonyl compoundsCarbonyl compounds.547.036547.05621046Takeda Takeshi1693627MiAaPQMiAaPQMiAaPQBOOK9910830654803321Modern carbonyl olefination4071569UNINA