04957nam 2200613 a 450 991083050950332120230213211645.01-280-76859-297866136793690-470-71920-60-470-71671-1(CKB)1000000000687620(EBL)703766(SSID)ssj0000715101(PQKBManifestationID)11410193(PQKBTitleCode)TC0000715101(PQKBWorkID)10701285(PQKB)11568008(MiAaPQ)EBC703766(OCoLC)264615452(EXLCZ)99100000000068762019850814h19611960 uy 0engur|n|---|||||txtccrCiba Foundation Symposium jointly with Committee for Symposia on Drug Action, on Adrenergic Mechanisms[electronic resource] /editor for the British Pharmacological Society, J.R. Vane ; editors for the Ciba Foundation, G.E.W. Wolstenholme and Maeve O'ConnorBoston Little, Brown and Co.[1961? c1960]1 online resource (666 p.)Ciba Foundation symposiaDescription based upon print version of record.0-470-72264-9 Includes bibliographical references and indexes.ADRENERGIC MECHANISMS; CONTENTS; Opening address; Session 1 : Formafion and lnactivation of Adrenergic Transmitters; Formation of adrenergic transmitters; Formation of adrenaline and noradrenaline; Discussion; The fate of adrenaline and noradrenaline; 3-Methoxy-4-hydroxymandelic acid excretion in phaeochromocytoma; The metabolism of [α-l4CJ](±)-adrenaline in the cat; Discussion; Session 2: Storage of Catechol Aminer; Chairman's opening remarks; Origin, development and distribution of chromaffin cells; The storage of amines in the chromaffin cellSome observations on the synthesis and storage of catechol amines in the adrenaline-containing cells of the suprarenal medullaCell types of the adrenal medulla; Discussion; Session 3: The Adrenergic Neurone; Chairman's opening remarks; Release of sympathetic transmitter by nerve stimulation; Discussion; Interference with the release of transmitter in response to nerve stimulation; The effects of bretylium and allied agents on adrenergic neurones; The persistence of adrenergic nerve conduction after TM 10 or bretylium in the cat; Some pharmacological properties of guanethidine; DiscussionSession 4: Adrenergic Mechanisms in ManEffects of adrenaline, noradrenaline and isopropylnoradrenaline in man; Effects of catechol amines on consecutive vascular sections; Discussion; Clinical effects of drugs which prevent the release of adrenergic transmitter; Bretylium; Discussion; Session 5 : Actions of Adrenaline and Noradrenaline on the Effector Cell; Chairman's opening remarks: The concept of receptors; Relationships between agonists, antagonists and receptor sites; Receptors for sympathomimetic amines; Sympathomimetic drugs and their receptorsVarious types of receptors for sympathomimetic drugsDiscussion; Biophysical changes produced by adrenaline and noradrenaline; Effect of adrenaline on depolarized smooth muscle; Discussion; The relation of adenosine-3',5'-phosphate to the action of catechol amines; The action of adrenaline on carbohydrate metabolism in relation to some of its pharmacodynamic efficts; Discussion; Session 6: Mechanism of Action of Other Sympathortiimetic Amines; Chairman's opening remarks; Tyramine and other amines as noradrenaline-releasing substances; Some observations on the effects of tyramine; DiscussionThe actions of sympathomimetic amines on tryptamine receptorsThe depolarizing and blocking action of amphetamine in the cat's superior cervical ganglion; Discussion; Session 7: Central Adrenergic Mechanisms; Chairman's opening remarks; Some central actions of adrenaline and noradrenaline when administered into the cerebral ventricles; Intervention of an adrenergic mechanism during brain stem reticular activation; Electrophysiological evidence relating to the rôle of adrenaline in the central nervous system; The passage of catechol amines through the blood-brain barrierRelease of an adrenaline-like substance by electrical stimulation of the brain stemCiba Foundation symposium.Adrenergic mechanismsCongressesAdrenergic mechanisms612.45082Vane John R95892O'Conner Maeve1275287Wolstenholme G. E. W(Gordon Ethelbert Ward)63039MiAaPQMiAaPQMiAaPQBOOK9910830509503321Ciba Foundation Symposium jointly with Committee for Symposia on Drug Action, on Adrenergic Mechanisms3005068UNINA