02743oam 2200601zu 450 991083034180332120210721055542.097866105561200-470-86873-2(CKB)111087027093264(SSID)ssj0000161654(PQKBManifestationID)11164483(PQKBTitleCode)TC0000161654(PQKBWorkID)10199616(PQKB)10848549(MiAaPQ)EBC5247714(Au-PeEL)EBL5247714(CaONFJC)MIL55612(OCoLC)748537746(EXLCZ)9911108702709326420160829d2002 uy engurcnu||||||||txtccrThe genetics and biology of sex determination[Place of publication not identified]John Wiley20021 online resource (275 pages)Bibliographic Level Mode of Issuance: Monograph0-470-84346-2 Nature employs a wide variety of sex determining mechanisms and it is only comparatively recently that the tools have become available for these to be explored at the cellular and molecular levels. A major landmark was the discovery in 1990 of the SRY gene and the subsequent demonstration of its key role in triggering male sex determination in transgenic mice. This book reviews and discusses our current understanding of the molecular genetic pathways of sex determination, with special emphasis on vertebrates. It features comparisons with other modes of sex determination, consideration of the biology of sexual development and discussion of the evolution of sex-determining mechanisms. By bringing together an international and interdisciplinary group of experts who study many different aspects of the problem, the book highlights much new and exciting work in this area and serves to identify and stimulate promising new research directions.Genetic sex determinationCongressesSex Determination ProcessesPhysiologyHILCCHuman Anatomy & PhysiologyHILCCHealth & Biological SciencesHILCCCongress.Genetic sex determinationSex Determination Processes.PhysiologyHuman Anatomy & PhysiologyHealth & Biological Sciences571.882Goode JamieNovartis FoundationChadwick DerekNovartis FoundationPQKBBOOK9910830341803321The genetics and biology of sex determination4084487UNINA