03980nam 2200625Ia 450 991083028600332120230725025420.01-282-88971-097866128897143-527-63326-X3-527-63324-33-527-63325-1(CKB)2670000000055453(EBL)602643(OCoLC)699474437(SSID)ssj0000477765(PQKBManifestationID)11326961(PQKBTitleCode)TC0000477765(PQKBWorkID)10512932(PQKB)10076884(MiAaPQ)EBC602643(EXLCZ)99267000000005545320100129d2011 uy 0engur|n|---|||||txtccrMonolithic silicas in separation science[electronic resource] concepts, syntheses, characterization, modeling and applications /edited by Klaus K. Unger, Nobuo Tanaka, and Egidijus MachtejevasWeinheim Wiley-VCHc20111 online resource (364 p.)Description based upon print version of record.3-527-32575-1 Includes bibliographical references and index.Monolithic Silicas in Separation Science; Contents; Preface; List of Contributors; 1: The Basic Idea and the Drivers; 1.2: Monoliths as Heterogeneous Catalysts; 1.3: Monoliths in Chromatographic Separations; 1.4: Conclusion and Perspectives; References; Part One: Preparation; 2: Synthesis Concepts and Preparation of Silica Monoliths; 3: Preparation and Properties of Various Types of Monolithic Silica Stationary Phases for Reversed-Phase, Hydrophilic Interaction, and Ion-Exchange Chromatography Based on Polymer-Coated Materials; Part Two: Characterization and Modeling4: Characterization of the Pore Structure of Monolithic Silicas5: Microscopic Characterizations; 6: Modeling Chromatographic Band Broadening in Monolithic Columns; 7.1: Introduction; 7.2: Basic Columns Properties; 7.3: Comparison of the Through-Pore Structures and Related Properties; 7.4: Thermodynamic Properties; 7.5: Kinetic Properties and Column Efficiency; 7.6: Conclusions; Part Three: Applications; 8: Quantitative Structure-Retention Relationships in Studies of Monolithic Materials; 9: Performance of Silica Monoliths for Basic Compounds. Silanol Activity; 10: Quality Control of Drugs11: Monolithic Stationary Phases for Fast Ion Chromatography12: Monolithic Chiral Stationary Phases for Liquid-Phase Enantioseparation Techniques; 13: High-Speed and High-Efficiency Separations by Utilizing Monolithic Silica Capillary Columns; 14: Silica Monolithic Columns and Mass Spectrometry; 15: Silica Monoliths for Small-Scale Purification of Drug-Discovery Compounds; 16: Monolithic Silica Columns in Multidimensional LC-MS for Proteomics and Peptidomics; 17.1: Introduction; 17.2: Extraction Process; 17.3: Extraction Platforms; 17.4: Applications; 17.5: Conclusion and Outlook; ReferencesIndexEdited by the experts and pioneers in the field, this is the first monograph to cover the topic, containing the must-have information hitherto only scattered among journals.Clearly divided into sections on preparation, characterization and modeling, and applications, this is essential reading for chemists, chromatographers, analytical chemists, biochemists and biologists.Separation (Technology)SilicaSeparation (Technology)Silica.546.68546.683Machtejevas Egidijus1715391Tanaka Nobuo96771Unger K. K(Klaus K.),1936-273428MiAaPQMiAaPQMiAaPQBOOK9910830286003321Monolithic silicas in separation science4109987UNINA