02701nam 2200613 450 991078806990332120211111232642.00-12-802528-X(CKB)2670000000574775(OCoLC)899002651(CaPaEBR)ebrary10976677(SSID)ssj0001407512(PQKBManifestationID)11807517(PQKBTitleCode)TC0001407512(PQKBWorkID)11411654(PQKB)10957097(Au-PeEL)EBL1844197(CaPaEBR)ebr10976677(CaONFJC)MIL659046(OCoLC)895660720(CaSebORM)9780128022580(MiAaPQ)EBC1844197(EXLCZ)99267000000057477520141124h20152015 uy 0engurcnu||||||||txtccrArchitecting high performing, scalable and available enterprise web applications /Shailesh Kumar Shivakumar1st editionWaltham, Massachusetts :Morgan Kaufmann,2015.©20151 online resource (288 p.)Bibliographic Level Mode of Issuance: Monograph0-12-802258-2 1-322-27766-4 Includes bibliographical references.Architecting High Performing, Scalable and Available Enterprise Web Applications provides in-depth insights into techniques for achieving desired scalability, availability and performance quality goals for enterprise web applications. The book provides an integrated 360-degree view of achieving and maintaining these attributes through practical, proven patterns, novel models, best practices, performance strategies, and continuous improvement methodologies and case studies. The author shares his years of experience in application security, enterprise application testing, caching techniques, production operations and maintenance, and efficient project management techniques--From publisher description.Enterprise application integration (Computer systems)Web applicationsDevelopmentWeb applicationsInternet marketingEnterprise application integration (Computer systems)Web applicationsDevelopment.Web applicationsInternet marketing.658.4038028553Shivakumar Shailesh Kumar849514MiAaPQMiAaPQMiAaPQBOOK9910788069903321Architecting high performing, scalable and available enterprise web applications3721902UNINA05355nam 2200661 a 450 991083020500332120230725052454.03-527-64206-41-283-30244-697866133024413-527-63274-33-527-63273-5(CKB)3400000000000394(EBL)700896(OCoLC)758389527(SSID)ssj0000506358(PQKBManifestationID)11344040(PQKBTitleCode)TC0000506358(PQKBWorkID)10530064(PQKB)11196378(MiAaPQ)EBC700896(EXLCZ)99340000000000039420111128d2010 uy 0engur|n|---|||||txtccrBiomechanics of hard tissues[electronic resource] modeling, testing, and materials /edited by Andreas Öchsner and Waqar Ahmed4th ed.Weinheim [Germany] Wiley-VCH Verlag GmbH & Co.20101 online resource (324 p.)Description based upon print version of record.3-527-32431-3 Includes bibliographical references and index.Biomechanics of Hard Tissues: Modeling, Testing, and Materials; Contents; Preface; List of Contributors; 1 Bone and Cartilage - its Structure and Physical Properties; 1.1 Introduction; 1.1.1 The Structure of Living Organisms; 1.1.2 Growth of Living Organisms; 1.1.2.1 Ring-Shaped Grain Boundary; 1.1.3 Planarity of Biological Structures; 1.2 Macroscopic Structure of the Bone; 1.2.1 Growth of the Bone; 1.2.2 Structure of the Body; 1.2.3 Macroscopic Structure of Skeleton; 1.2.4 Apatite in the Bone; 1.2.5 Structure of the Bone; 1.3 Microscopic Structure of the Bone; 1.3.1 General; 1.3.2 Osteon1.3.3 Bone Innervation1.3.3.1 Anatomy of Bone Innervation; 1.3.4 Bone Cells; 1.3.4.1 Cells; 1.3.4.2 Cell Membrane; 1.3.4.3 Membrane Transport; 1.3.4.4 Bone Cell Types; 1.3.4.5 Osteoclasts; 1.3.5 Cellular Image - OPG/RANK/RANKL Signaling System; 1.3.5.1 Osteoprotegerin; 1.3.5.2 RANK/RANKL; 1.3.5.3 TACE; 1.3.5.4 Bone Modeling and Remodeling; 1.3.6 Proteins and Amino Acids; 1.3.7 Collagen and its Properties; 1.3.7.1 Molecular Structure; 1.3.8 Geometry of Triple Helix; 1.3.9 Polymer Thermodynamics; 1.3.9.1 Thermodynamics; 1.3.9.2 Ideal Chain; 1.3.9.3 Wormlike Chain1.3.9.4 Architecture of Biological Fibers1.3.9.5 Architecture of Collagen Fibers in Human Osteon; 1.3.9.6 Collagen Elasticity; 1.4 Remarks and Conclusions; 1.5 Comments; 1.6 Acknowledgments; References; Further Reading; 2 Numerical Simulation of Bone Remodeling Process Considering Interface Tissue Differentiation in Total Hip Replacements; 2.1 Introduction; 2.2 Mechanical Adaptation of Bone; 2.3 Constitutive Models; 2.3.1 Bone Constitutive Model; 2.3.2 Interface Constitutive Model; 2.3.3 Model for Periprosthetic Adaptation; 2.3.4 Model for Interfacial Adaptation; 2.4 Numerical Examples2.5 Final Remarks2.6 Acknowledgments; References; 3 Bone as a Composite Material; 3.1 Introduction; 3.2 Bone Phases; 3.2.1 Organic; 3.2.2 Mineral; 3.2.3 Physical Structure of Bone Material; 3.2.4 Water; 3.3 Bone Phase Material Properties; 3.3.1 Organic Matrix; 3.3.2 Mineral Phase; 3.3.3 Water; 3.3.4 Elastic Modulus of Composite Materials; 3.4 Bone as a Composite: Macroscopic Effects; 3.5 Bone as a Composite: Microscale Effects; 3.6 Bone as a Composite: Anisotropy Effects; 3.7 Bone as a Composite: Implications; References4 Mechanobiological Models for Bone Tissue. Applications to Implant Design4.1 Introduction; 4.2 Biological and Mechanobiological Factors in Bone Remodeling and Bone Fracture Healing; 4.2.1 Bone Remodeling; 4.2.2 Bone Fracture Healing; 4.3 Phenomenological Models of Bone Remodeling; 4.4 Mechanistic Models of Bone Remodeling; 4.5 Examples of Application of Bone Remodeling Models to Implant Design; 4.6 Models of Tissue Differentiation. Application to Bone Fracture Healing; 4.7 Mechanistic Models of Bone Fracture Healing4.8 Examples of Application of Bone Fracture Healing Models to Implant DesignThis monograph assembles expert knowledge on the latest biomechanical modeling and testing of hard tissues, coupled with a concise introduction to the structural and physical properties of bone and cartilage. A strong focus lies on the current advances in understanding bone structure and function from a materials science perspective, providing practical knowledge on how to model, simulate and predict the mechanical behavior of bone. The book presents directly applicable methods for designing and testing the performance of artificial bones and joint replacements, while addressing innovativeHuman mechanicsMusculoskeletal systemMechanical propertiesBiomechanicsHuman mechanics.Musculoskeletal systemMechanical properties.Biomechanics.617.47Öchsner Andreas317948Ahmed Waqar948864MiAaPQMiAaPQMiAaPQBOOK9910830205003321Biomechanics of hard tissues4082573UNINA