03610nam 2200673Ia 450 991083019890332120230331005406.01-282-34759-497866123475970-470-51375-60-470-51376-4(CKB)1000000000377135(EBL)470464(OCoLC)609849369(SSID)ssj0000297325(PQKBManifestationID)11253858(PQKBTitleCode)TC0000297325(PQKBWorkID)10332438(PQKB)11519158(MiAaPQ)EBC470464(EXLCZ)99100000000037713519890130d1989 uy 0engur|n|---|||||txtccrGenetic analysis of tumour suppression[electronic resource]Chichester ;New York Wiley19891 online resource (270 p.)Ciba Foundation symposium ;142Proceedings of a symposium held at the Ciba Foundation, London, July 19-21, 1988.Editors, Greg Bock, Joan Marsh."A Wiley-Interscience publication."0-471-92299-4 Includes bibliographies and indexes.GENETIC ANALYSIS OF TUMOUR SUPPRESSION; Contents; Participants; Introduction; Epidemiology of genetically determined cancer; Transgenic mice and host cell mutants resistant to transformation as model systems for identifying multiple components in oncogenesis; Reversion of tumorigenicity in an EBV-converted Burkitt's lymphoma line; Lymphoid neoplasia and the control of haemopoietic differentiation; General discussion I; Loss of genetic information in cancer; General discussion II; The molecular basis of retinoblastomas; General discussion IllProviral position effects: possible probes for genes that suppress transcriptionGeneral discussion IV; Flat revertants of EJ human bladder carcinoma cells show two different mechanisms of reversion; A genetic basis for tumour suppression; Molecular basis for the regulation of cell fate by the lethal (2) giant larvae tumour suppressor gene of Drosophila melanogaster; Suppression of genetic melanoma in the fish Xiphophorus; The biology of tumour suppression; General discussion V; Cell differentiation and tumour suppression; General discussion VI; Final discussion; Index of contributorsSubject indexComprises the proceedings of a symposium held at the Ciba Foundation, London, February 1988. Contains the latest research results on the inverse relationship between cell proliferation and differentiation and the nature of the genes involved. Included are the studies of cell fusion experiments, the introduction of single chromosomes into malignant cells, and the transfection of individual genes. Also reports on the role of certain oncogenes in normal development, lineage commitment, and tumorigenesis.Ciba Foundation symposium ;142.TumorsGenetic aspectsCongressesGene expressionCongressesOncogenesCongressesTumorsGenetic aspectsGene expressionOncogenes616.99616.994042Bock Gregory322650Marsh Joan91633Ciba Foundation.MiAaPQMiAaPQMiAaPQBOOK9910830198903321Genetic analysis of tumour suppression4082531UNINA