03590nam 2200613 a 450 991083019200332120230331005358.01-282-34770-597866123477020-470-51406-X0-470-51407-8(CKB)1000000000377207(EBL)470463(OCoLC)814417854(SSID)ssj0000291795(PQKBManifestationID)11223129(PQKBTitleCode)TC0000291795(PQKBWorkID)10255383(PQKB)10726737(MiAaPQ)EBC470463(EXLCZ)99100000000037720719901029d1991 uy 0engur|n|---|||||txtccrClinical applications of TGF-[beta][electronic resource]Chichester ;New York Wiley19911 online resource (266 p.)Ciba Foundation symposium ;157Based on the Symposium on Clinical Applications of TGF-[beta], held at the Ciba Foundation, London, June 12-14, 1990.Editors: Gregory R. Bock and Joan Marsh."A Wiley-Interscience publication."0-471-92811-9 Includes bibliographical references and indexes.CLINICAL APPLICATIONS OF TGF-B; Contents; Introduction; Multiple forms of TGF-B: distinct promoters and differential expression; TGF-B receptors; Mechanisms in TGF-B action; Regulation of epithelial proliferation by TGF-B; Latent forms of TGF-B: molecular structure and mechanisms of action; General discussion I : The role of TGF-B in the nervous system; TGF-B: a possible autocrine immune regulator; TGF-B and wound healing; General discussion II : A stimulatory effect of transforming growth factors on skin tumour devdopmcnt in vivo; The effects of TGF-B on boneTGF-B1 and fibroblast growth factors selectively up-regulate tissue-specific fetal genes in cardiac muscle cellsEffects of TGF-Bs in the liver : cell proliferation and fibrogenesis; Role of TGF-B1 in experimental glomerulonephritis; The role of TGF-B in pulmonary fibrosis; In vivo and in vitro effects of TGF-B1 on normal and neoplastic haemopoiesis; Expression of TGF-B2 in human glioblastoma : a role in resistance to immune rejection?; Index of contributors; Subject indexTGF-beta, originally identified as a transforming growth factor with similar properties, is now known to exist as a family of factors with similar properties. These factors promote cell proliferation in some tissue types or conditions and induce cell differentiation in others. Features the latest information on the TGF-beta family and its receptors. Describes correlations between TGF-beta and certain cancers, including glioblastomas. Also contains reports of preliminary investigations of clinical applications for TGF-beta in many diseases, including leukemia and its use to accelerate wound heaCiba Foundation symposium ;157.Transforming growth factors-betaTherapeutic useCongressesTransforming growth factors-betaTherapeutic use574.88615.7Bock Gregory322650Marsh Joan91633Symposium on Clinical Applications of TGF-[beta](1990 :Ciba Foundation)MiAaPQMiAaPQMiAaPQBOOK9910830192003321Clinical applications of TGF-4039996UNINA