05328nam 2200745Ia 450 991083014290332120170815154012.01-282-30164-097866123016430-470-18688-70-470-18836-7(CKB)1000000000376544(EBL)469645(OCoLC)814416086(SSID)ssj0000388137(PQKBManifestationID)11284268(PQKBTitleCode)TC0000388137(PQKBWorkID)10411423(PQKB)10636340(SSID)ssj0000360399(PQKBManifestationID)11253385(PQKBTitleCode)TC0000360399(PQKBWorkID)10326196(PQKB)10906194(MiAaPQ)EBC469645(PPN)241443156(EXLCZ)99100000000037654420070725d1971 uy 0engur|n|---|||||txtccrFused pyrimidinesPart two[electronic resource] /edited by D. J. Brown99th ed.New York Wiley-Interscience19711 online resource (684 p.)Chemistry of heterocyclic compounds ;v. 24, pt. 2Description based upon print version of record.0-471-38205-1 Includes bibliographical references and index.FUSED PYRIMIDINES: PURINES; Contents; Tables; I. Introduction to the Purines; 1. History; TABLE 1. Trivial Names of Purines; 2. Nomenclature and Notation; 3. The Basis of Purine Chemistry; A. The Electrophilic Character of the 2-, 6- and 8-Carbon Atoms; B. The Nucleophilic Character of the 8-Carbon Atom; C. Tautomeric Groups; 4. General Summary of Purine Chemistry; A. Electrophilic Substitution; (a) Nitration; (b) Diazo Coupling; (c) Halogenation; (d) Alkylation; B. Nucleophilic Substitution; (a) Halogen Replacement by Amino Groups; (b) Halogen Replacement by Methoxy and Other Alkoxy Groups(c) Halogen Replacement by Oxo Group(d) Halogen Replacement by Alkylthio Groups; (e) Halogen Replacement by Thio Group; (f) Halogen Replacement by Thiocyanato and Cyano Groups; (g) Halogen Replacement by Sulpho Groups; (h) Replacement of Methoxy, Methylthio, and Methylsulphonyl Groups; C. Group Interconversion; (a) Interchange of Halogen Atoms; (b) Oxo- to Aminopurines; (c) Oxo- to Chloropurines; (d) Oxo- to Thiopurines; (e) Thio- (and Methylthio-) to Oxopurines; (f) Thio- (and Methylthio-) to Halogenopurines; (g) Thio- to Aminopurines; (h) Interchange of Amino Groups(i) Amino- to Oxopurines(j) Amino- to Halogenopurines; D. Addition Reactions; (a) The Michael Reaction; (b) Quaternisation; (c) Formation of N-Oxides; (d) Addition of Water and Alcohols; E. Modification of Substituents; (a) Amino Groups; (b) Oxo Groups; (c) Thio Groups; (d) Methyl Groups; F. Reductive Reactions; (a) Nuclear Reduction; (b) Removal of Groups; (c) Reductive Modification of Groups; G. Oxidative Reactions; (a) Chemical Oxidation; (b) Free Radical Attack; (c) Enzymic Oxidation; 5. Physical Properties of Purines; A. Electronic Considerations; B. Ionisation ConstantsC. Crystal StructureD. Dipole Moments; E. Polarography; F. Solubility and Melting Point; G. Spectra; Chapter II. Syntheses from Pyrimidines; 1. Use of 4,5-Diaminopyrimidines (The Traube Synthesis); A. History and General Application; B. Cyclisation with Formic Acid; C. Cyclisation with Dithioformic Acid; D. Cyclisation with Other Carboxylic Acids; E. Cyclisation with Acid Anhydride; F. Cyclisation with Acid Chlorides; G. Cyclisation with Orthoesters and Diethoxymethyl AcetateTABLE 2. Cyclisation of 4,5-Diamino-6-dimethylamino-2-methylthiopyrimidine to 6-dimethylamino-2-methylthiopurine with OrthoestersH. Cyclisation with Formamide; I. Cyclisation with Other Amides; J. Cyclisation with NN-Dialkylamides and Phosphoryl Chloride; K. Cyclisation with Amidines; L. Cyclisation with Guanidines; M. Cyclisation with Urea; N. Cyclisation with Thiourea; O. Cyclisation with Cyanates, Isocyanates, and Derivatives; P. Cyclisation with lsothiocyanates; Q. Cyclisation with Carbon Dioxide; R. Cyclisation with Carbon Disulphide; S. Cyclisation with PhosgeneT. Cyclisation with ThiophosgeneChemistry of Heterocyclic Compounds publishes articles, letters to the Editor, reviews, and minireviews on the synthesis, structure, reactivity, and biological activity of heterocyclic compounds including natural products. The journal covers investigations in heterocyclic chemistry taking place in scientific centers of all over the world, including extensively the scientific institutions in Russia, Ukraine, Latvia, Lithuania and Belarus.Chemistry of heterocyclic compounds ;v. 24, pt. 2.PyrimidinesChemistryPyrimidines.Chemistry.547.593547/.59/05547/.596Lister John H(John Henry)958395Brown D. J383088MiAaPQMiAaPQMiAaPQBOOK9910830142903321Fused pyrimidines3984779UNINA