03651nam 2200625 a 450 991083005970332120230331005356.01-282-34600-897866123460020-470-51348-90-470-51349-7(CKB)1000000000377311(EBL)470679(OCoLC)609849686(SSID)ssj0000289519(PQKBManifestationID)11911073(PQKBTitleCode)TC0000289519(PQKBWorkID)10402998(PQKB)10120410(MiAaPQ)EBC470679(EXLCZ)99100000000037731119870402d1987 uy 0engur|n|---|||||txtccrAutoimmunity and autoimmune disease[electronic resource]Chichester ;New York Wiley19871 online resource (290 p.)Ciba Foundation symposium ;129Editors: David Evered (organizer) and Julie Whelan."Symposium on Autoimmunity and Autoimmune Disease, held at the Ciba Foundation, London, 30 September-2 October 1986"--Contents p."A Wiley-Interscience publication."0-471-91095-3 Includes bibliographical references and indexes.AUTOIMMUNITY AND AUTOIMMUNE DISEASE; Contents; Participants; Introduction; Cardiac myosin and autoimmune myocarditis; Intracellular autoantigens: diagnostic fingerprints but aetiological dilemmas; Significance of carbohydrate components of cell surfaces; How is tolerance generated?; Therapeutic immune regulation in experimental interstitial nephritis with suppressor T cells and their soluble factors; Regulation of HL4 class II expression and its role in autoimmune disease; Id iotypes and autoimmunityMolecular basis for the cross-reactive idiotypes on human anti-lgG autoanti bodies (rheumatoid factors)Autoimmunity and immunodeficiency disease; Deficiency of the effector mechanisms of the immune response and au toimmu n ity; General discussion; Monoclonal anti-la antibody therapy in animal models of autoimmune disease; Monoclonal antibodies for the depletion of specific subpopulations of lymphocytes; Manipulation of idiotype networks in autoimmunity; Interferons: cytokines in autoimmunity; Specific immunoabsorption; Final general discussion; Chairman's summing-up; Index of contributorsSubject IndexThis work focuses on the autoimmune processes that have now been proven to underlie a number of serious diseases, including diabetes mellitus, rheumatoid arthritis and multiple sclerosis. Papers explore the rapidly expanding developments in research on immune response and regulation, and their potential in the development of treatments for autoimmune diseases. The wide range of subjects covered here include: the nature of intracellular and cell surface-derived ``self'' antigens; competing theories of the generation of immune tolerance and their implications of current theories for research andCiba Foundation symposium ;129.Autoimmune diseasesCongressesAutoimmune diseases616.9616.978Evered David857127Whelan Julie322651Symposium on Autoimmunity and Autoimmune Disease(1986 :Ciba Foundation)MiAaPQMiAaPQMiAaPQBOOK9910830059703321Autoimmunity and autoimmune disease4116977UNINA