01302nam a2200289 i 450099100316556970753620020509113322.0010702s1998 de ||| | ger 3519075377b11118830-39ule_instPARLA176336ExLDip.to Filol. Class. e di Scienze FilosoficheitagergrcKramer, Bärbel403045Griechische Papyri der Staats- und Universitätsbibliothek Hamburg :(P. Hamb. IV) /herausgegeben von Bärbel Kramer und Dieter HagedornStuttgart :B.G. Teubner,1998xxi, 306 p. :ill. ;25 cm.Archiv für Papyrusforschung und verwandte Gebiete. Beiheft ;4Hagedorn, DieterStaats- und Universitätsbibliothek Hamburg.b1111883023-02-1728-06-02991003165569707536LE007 P A 1910/4V. 412007000056776le007-E133.00-l- 00000.i1125638228-06-02LE007 P A 1919/4 bisV. 412007000063323le007-E133.67-l- 00000.i1253821826-06-03Griechische Papyri der Staats- und Universitätsbibliothek Hamburg858329UNISALENTOle00701-01-01ma -gerde 0100983nam a2200253 i 4500991001518479707536111202s2010 it 000 0 ita d88141546359788814154638b14027197-39ule_instDip.to Studi Giuridiciita342.45042Annuario DRASD 2010 :dottorato di ricerca autonomie locali, servizi pubblici e diritti di cittadinanza /a cura di Renato BalduzziMilano :Giuffrè,2010xii, 344 p. ;24 cmMemorie della facoltà di giurisprudenza.Ser. 2. ;33Autonomia localeBalduzzi, Renato.b1402719702-04-1402-12-11991001518479707536LE027 346.45 DRA01.01201012027000321148le027pE56.00-n- 180000.i1543864828-08-12Annuario DRASD 2010243573UNISALENTOle02702-12-11ma -itait 2005264nam 2200613Ia 450 991082994700332120230617041758.01-280-85410-397866108541033-527-60779-X3-527-60701-3(CKB)1000000000377308(EBL)481606(OCoLC)70113548(SSID)ssj0000191609(PQKBManifestationID)11156543(PQKBTitleCode)TC0000191609(PQKBWorkID)10186628(PQKB)11000500(MiAaPQ)EBC481606(EXLCZ)99100000000037730820050902d2005 uy 0engur|n|---|||||rdacontentrdamediardacarrierLeukocyte trafficking[electronic resource] molecular mechanisms, therapeutic targets, and methods /edited by Alf Hamann and Britta EngelhardtWeinheim Wiley-VCHc20051 online resource (559 p.)Description based upon print version of record.3-527-31228-5 Includes bibliographical references and index.Leukocyte Trafficking; Contents; Preface; Acknowledgements; List of Authors; Color Plates; Part I Molecular Mechanisms; 1 The Multistep Model of Leukocyte Trafficking: A Personal Perspective from 15 Years Later; Acknowledgments; References; 2 Capture and Rolling: Selectins and Their Ligands; 2.1 Introduction; 2.2 Selectins; 2.2.1 L-Selectin; 2.2.2 P-Selectin; 2.2.3 E-Selectin; 2.3 P-Selectin Glycoprotein Ligand 1 and Other Ligands of Selectins; 2.4 Glycosyltransferases; References; 3 Chemokines and Their Receptors: Biochemical, Structural and Biological Properties; 3.1 Introduction3.2 Chemokines3.3 Chemokine Receptors; 3.4 Role of Chemokines in Lymphocyte and Dendritic Cell Trafficking to and Within Primary and Secondary Lymphoid Organs; 3.4.1 Primary Lymphoid Organs; 3.4.1.1 Bone Marrow; 3.4.1.2 Thymus; 3.4.2 Secondary Lymphoid Organs; 3.4.2.1 Spleen; 3.4.2.2 Lymph Nodes; 3.4.2.3 Mucosa-Associated Lymphoid Tissue; Acknowledgments; References; 4 Mechanisms of Leukocyte Integrin Activation; 4.1 Introduction; 4.2 Modalities of Integrin Activation and the Role of Chemokines; 4.3 Signaling Mechanisms Controlling Rapid Integrin Activation4.4 Chemokines, Integrins and Concurrency in Leukocyte Recruitment4.5 The Way Ahead; References; 5 Mechanisms of Leukocyte Transmigration: Role of Immunoglobulin Superfamily Molecules; 5.1 Introduction; 5.2 Leukocyte Migration Through Endothelial Cells; 5.3 Endothelial Cell Junctional Molecules; 5.4 Role of Immunoglobulin Superfamily Cell Adhesion Molecules in Leukocyte Transmigration; 5.5 Intercellular Adhesion Molecules; 5.5.1 Structure, Ligands, and Expression Profile; 5.5.2 Role in Leukocyte Transmigration; 5.5.3 Signaling by ICAM-1 and ICAM-2; 5.6 Junctional Adhesion Molecules5.6.1 Structure, Ligands, and Expression Profile5.6.2 Role in Leukocyte Transmigration; 5.6.3 Signaling by JAMs; 5.7 PECAM-1 (CD31); 5.7.1 Structure, Ligands, and Expression Profile; 5.7.2 Role in Leukocyte Transmigration; 5.7.3 Signaling by PECAM-1; 5.8 Role of Additional Molecules in Regulation of Leukocyte Transmigration; 5.8.1 T Cell Receptor; 5.8.2 CD99; 5.9 Summary and Future Directions; Acknowledgments; References; 6 The Endothelial Cell Basement Membrane and Its Role in Leukocyte Extravasation; 6.1 Introduction; 6.2 Extracellular Matrix of Blood Vessels; 6.2.1 Basement Membranes6.2.2 Laminins6.3 Function of Endothelial Cell Basement Membranes; 6.3.1 Leukocyte Adhesion and Migration Studies; 6.3.2 Methods of Investigation of Leukocyte Migration on Extracellular Matrix Substrates; 6.3.3 Murine Inflammatory Models; 6.3.4 Role of Proteases; 6.4 Conclusion; Acknowledgment; References; Part II Trafficking in vivo; 7 Control of Homing Receptor Expression during Lymphocyte Differentiation, Activation, and Function; 7.1 Introduction; 7.2 Developing Lymphocytes Undergo Programmed Changes in Homing Receptor Expression7.3 Control of Homing Receptor Expression During Lymphocyte Activation and Effector Cell DifferentiationWritten by known specialists in the field, this is a comprehensive and timely overview of a central and expanding topic. Simultaneously an introduction and a description of the latest concepts, findings and methods, the handbook provides basic knowledge on technical issues required for those intending to research in the field. It covers the functional role of involved molecules and the cellular mechanisms, and addresses selected examples for their possible application in therapy -- bridging the gap between trafficking mechanisms and novel therapeutic strategies. In addition, it includes selectLeucocytesImmunologyLeucocytes.Immunology.571.96Hamann Alf1634249Engelhardt Britta1634250MiAaPQMiAaPQMiAaPQBOOK9910829947003321Leukocyte trafficking3974379UNINA