04616nam 2200745 a 450 991082825480332120240516065040.09786613694393978128078400212807840089780470720691047072069797804707183840470718382(CKB)1000000000688140(EBL)703908(OCoLC)797918484(SSID)ssj0000715483(PQKBManifestationID)11400816(PQKBTitleCode)TC0000715483(PQKBWorkID)10706051(PQKB)11381396(MiAaPQ)EBC703908(Au-PeEL)EBL703908(CaPaEBR)ebr10575608(CaONFJC)MIL369439(Perlego)2771421(EXLCZ)99100000000068814019820514d1982 uy 0engur|n|---|||||txtrdacontentcrdamediacrrdacarrierMetabolic acidosis /[editors, Ruth Porter, Geralyn Lawrenson]1st ed.London Pitman ;Summit, N.J. distributed in North America by CIBA Pharmaceutical Co.19821 online resource (406 pages)Ciba Foundation symposium ;87 (new ser.)Symposium on Metabolic Acidosis, held at the Ciba Foundation, London, 12-14 May 1981.9780470663974 0470663979 9780272796511 0272796514 Includes bibliographical references and indexes.Metabolic acidosis; Contents; The hydrogen ion in normal metabolism; Discussion; The techniques and uses of intracellular pH measurements; Discussion; Energy metabolism and cellular pH in normal and pathological conditions. A new look through 31phosphorus nuclear magnetic resonance; Discussion; Acidosis and contractility of heart muscle; Discussion; Lactic acidosis in the brain: occurrence, triggering mechanisms and pathophysiological importance; Discussion; Glutamine metabolism in metabolic acidosis; Discussion; The regulation of ketogenesis; Discussion; General discussion IFasting and ketone body metabolism Metabolic acidosis in exercise: (i) The fate of carboxylate ions during exercise; (ii) Clinical measurements of lactate loads; Preliminary observations on the metabolic responses to exercise in humans, using 31phosphorus nuclear magnetic resonance; Discussion; Metabolic acidosis and changes in water and electrolyte balance after maximal exercise; Some hormonal influences on glucose and ketone body metabolism in normal human subjects; Discussion; Effects of free fatty acids, insulin, glucagon and adrenaline on ketone body production in humans; DiscussionQuantitative aspects of L(+)-lactate metabolism in human beings Discussion; The role of catecholamines in metabolic acidosis; Discussion; Acid-base balance in diabetic ketoacidosis; Discussion; Isotope turnover studies in uncontrolled diabetes and the effects of insulin; Discussion; Metabolic acidosis in the critically ill; Discussion; The role of altered lactate kinetics in the pathogenesis of Type B lactic acidosis; Discussion; Organic acidurias: approach, results and clinical relevance; Discussion; Problems in the congenital lactic acidoses; Discussion; GENERAL DISCUSSION IIRegulation of energy metabolism, gluconeogenesis and ketogenesis The role of lactate in exercise; The relationship between intracellular and extracellular pH; Hormonal regulation of ketogenesis; Treatment of metabolic acidosis; Chairman's summary; Appendix; Index of contributors; Subject indexThe Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. Ciba Foundation symposium ;new ser. 87.AcidosisCongressesMetabolismDisordersCongressesAcidosisMetabolismDisorders616.3/99Porter Ruth64811Collins Geralyn M868426MiAaPQMiAaPQMiAaPQBOOK9910828254803321Metabolic acidosis2150525UNINA