03733nam 2200721 a 450 991082787930332120240516065057.09786613694447978128078405712807840599780470720752047072075197804707184450470718447(CKB)1000000000688147(EBL)703914(OCoLC)797918497(SSID)ssj0000715492(PQKBManifestationID)11404031(PQKBTitleCode)TC0000715492(PQKBWorkID)10705474(PQKB)11482713(MiAaPQ)EBC703914(Au-PeEL)EBL703914(CaPaEBR)ebr10575499(CaONFJC)MIL369444(Perlego)2764229(EXLCZ)99100000000068814719830801d1983 uy 0engurcn|||||||||txtccrMobility and function in proteins and nucleic acids1st ed.London Pitman19831 online resource (369 p.)Ciba Foundation symposium ;93Description based upon print version of record.9780470664124 0470664126 9780272796573 0272796573 Includes bibliographical references and indexes.Mobility and J function in proteins and nucleic acids; Contents; Introduction; The role of mobility in the substrate binding and catalytic machinery of enzymes; Discussion; Ligand- induced conformational changes in proteins; Discussion; Mobility and active-site coupling in 2-0x0 acid dehydrogenase complexes; Discussion; The mobility of calcium- trigger proteins and its function; Discussion; Mobility and function in elastin and collagen; Discussion; Flexibility in tobacco mosaic virus; Discussion; The molecular basis of muscle contraction; DiscussionActin-induced changes in the dynamics of myosin subfragment-1 detected by nuclear magnetic resonance Discussion; Rotational dynamics of spin-labelled muscle proteins; Discussion; Cross-bridge movement in muscle and the conformation of the myosin hinge; Discussion; Nuclear magnetic resonance studies on structure and breathing dynamics of transfer RNA; Discussion; Triplet anisotropy decay measurements of DNA internal motion; Discussion; Conformations and flexibilities of histones and high mobility group (HMG) proteins in chromatin structure and function; DiscussionLocal and collective motions in protein dynamics Discussion; Soliton theory of protein dynamics; Discussion; Nuclear magnetic resonance studies of mobility in proteins; Discussion; Summary and outlook; FINAL GENERAL DISCUSSION; Closing remarks; Index of contributors; Subject indexThe Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. Ciba Foundation symposium ;93.Nucleic acidsCongressesProteinsCongressesNucleic acidsProteins574.87/328574.87328MiAaPQMiAaPQMiAaPQBOOK9910827879303321Mobility and function in proteins and nucleic acids1938555UNINA