05067nam 2200673Ia 450 991082787370332120240417000453.00-309-17037-01-280-18418-397866101841870-309-56573-1(CKB)111069351124296(OCoLC)57005524(CaPaEBR)ebrary10068398(SSID)ssj0000176888(PQKBManifestationID)11170154(PQKBTitleCode)TC0000176888(PQKBWorkID)10206980(PQKB)10900597(MiAaPQ)EBC3377165(Au-PeEL)EBL3377165(CaPaEBR)ebr10068398(OCoLC)923268733(EXLCZ)9911106935112429620040120d2001 uy 0engurcn|||||||||txtccrImmunization safety review thimerosal-containing vaccines and neurodevelopmental disorders /Kathleen Stratton, Alicia Gable, and Marie C. McCormick, editors ; Immunization Safety Review Committee, Board on Health Promotion and Disease Prevention, Institute of Medicine1st ed.Washington, D.C. ;[Great Britain] National Academy Pressc20011 online resource (136 p.) The Compass seriesBibliographic Level Mode of Issuance: Monograph0-309-07636-6 Includes bibliographical references.IMMUNIZATION SAFETY REVIEW -- Copyright -- Acknowledgments -- Contents -- Executive Summary -- PLAUSIBILITY ASSESSMENT -- Biological Plausibility -- Causality -- SIGNIFICANCE ASSESSMENT -- PUBLIC HEALTH RESPONSE -- Policy Review and Analysis -- Public Health and Biomedical Research -- Epidemiological Research -- Clinical Research -- Basic Science Research -- Communications -- SUMMARY -- REFERENCES -- Immunization Safety Review: Thimerosal-Containing Vaccines and Neurodevelopmental Disorders -- ORIGINS OF THE IMMUNIZATION SAFETY REVIEW PROJECT -- THE CHARGE TO THE COMMITTEE -- THE STUDY PROCESS -- THE FRAMEWORK FOR ASSESSING CAUSALITY -- UNDER REVIEW: THIMEROSAL-CONTAINING VACCINES AND NEURODEVELOPMENTAL DISORDERS -- Thimerosal in Vaccines -- Neurodevelopmental Disorders -- Autism -- Attention Deficit/Hyperactivity Disorder (ADHD) -- Speech or Language Delay -- PLAUSIBILITY ASSESSMENT -- Evidence Regarding Association: Biological Plausibility -- Mercury Toxicokinetics -- Comparisons of Ethylmercury and Methylmercury -- Health Effects of High-Dose Exposures to Thimerosal, Ethylmercury, and Methylmercury -- Health Effects of Low-Dose Exposures to Thimerosal and Methylmercury -- Investigations Related to Mercury and Heavy Metals in Children with Autism -- Application of Methylmercury Exposure Guidelines to Thimerosal Exposure from Vaccines -- Biological Plausibility Argument -- Evidence Regarding Association: Case Reports, Case Series, and Uncontrolled and Controlled Epidemiological Studies -- Case Reports and Case Series -- Epidemiological Studies -- CAUSALITY ARGUMENT -- SIGNIFICANCE ASSESSMENT -- Concern Regarding Neurodevelopmental Disorders -- Continued Exposure to Thimerosal -- Use of Thimerosal-Containing Vaccines in Other Countries -- Confusion from Changes in Hepatitis B Immunization Policy -- Trust in the Safety of Vaccines -- Conclusion.RECOMMENDATIONS REGARDING THE PUBLIC HEALTH RESPONSE -- Policy Review and Analysis -- Public Health and Biomedical Research -- Epidemiological Studies -- Clinical Studies -- Basic Science Studies -- Communications -- SUMMARY -- REFERENCES -- Appendix A Immunization Safety Review: Measles-Mumps-Rubella Vaccine and Autism Executive Summary -- OVERVIEW OF THE IMMUNIZATION SAFETY REVIEW PROJECT -- THE HYPOTHESIZED RELATIONSHIP BETWEEN MMR AND AUTISM -- PLAUSIBILITY ASSESSMENT -- SIGNIFICANCE ASSESSMENT -- RECOMMENDATIONS -- Public Health Response -- Policy Review -- Research Regarding MMR and ASD -- Communications -- General and Crosscutting Issues -- SUMMARY -- REFERENCES -- Appendix B Monday, July 16, 2001 Meeting Agenda -- Appendix C Thimerosal Content in Licensed Vaccines -- Appendix D Immunization Safety Review Committee Biosketches -- Board on Health Promotion Disease Prevention Liaison.Compass series (Washington, D.C.)VaccinationComplicationsDevelopmental disabilitiesEtiologyOrganomercury compoundsToxicologyVaccinationComplications.Developmental disabilitiesEtiology.Organomercury compoundsToxicology.614.593Stratton Kathleen R1593160Gable Alicia1606325McCormick Marie C1606326Institute of Medicine (U.S.).Immunization Safety Review Committee.MiAaPQMiAaPQMiAaPQBOOK9910827873703321Immunization safety review3932068UNINA