04157oam 2200733I 450 991082767440332120240313181321.09781040212318104021231X978042916585604291658549781439862582143986258310.1201/b14166 (CKB)2670000000341598(EBL)1153191(OCoLC)831118576(SSID)ssj0000835126(PQKBManifestationID)11462241(PQKBTitleCode)TC0000835126(PQKBWorkID)10989673(PQKB)11457115(Au-PeEL)EBL1153191(CaPaEBR)ebr10674487(CaONFJC)MIL502263(FINmELB)ELB141044(MiAaPQ)EBC1153191(EXLCZ)99267000000034159820180331d2013 uy 0engur|n|---|||||txtccrConnexin cell communication channels roles in the immune system and immunopathology /edited by Ernesto Oviedo-Orta, Brenda R. Kwak, William Howard Evans1st ed.Boca Raton, Fla. CRC Pressc2013Boca Raton :Taylor & Francis/CRC Press,2013.1 online resource (363 p.)Description based upon print version of record.9781439862575 1439862575 Includes bibliographical references.Front Cover; Contents; Preface; Editors; Contributors; Prequel: Gap Junctions, Hemichannels, and Cell-to-Cell Signalling; Chapter 1 - Communication in the Immune System by Connexin Channels; Chapter 2 - Gap Junctions and Connexins in the Hematopoietic-Immune System: Structural Considerations; Chapter 3 - Approaches for Studying the Role(s) of Gap Junctions in the Immune System; Chapter 4 - Gap Junctions in Antigen-Presenting Cells; Chapter 5 - Connect the Immune System: Roles of Gap Junctions in Antigen Presentation and T Cell ActivationChapter 6 - Gap Junctions and Connexins in the Immune Defense Against TumorsChapter 7 - Connexins in Atherosclerosis; Chapter 8 - Connexins in Lung Function and Inflammation; Chapter 9 - Effect of Oxidative Stress on Connexins in the Vasculature; Chapter 10 - Regulation of Gap Junctions and Cellular Coupling within the Microvasculature in Response to Acute Inflammation; Chapter 11 - Impact of Microglial Activation on Astroglial Connexin Expression and Function in Brain Inflammation; Chapter 12 - A Role for Connexins in Inflammatory Disorders of the EpidermisChapter 13 - Translating Basic Research on Cx43 Gap Junctions into Therapies for Reducing Scarring and Cardiac ArrhythmiaChapter 14 - Connexin-Based Therapeutic Approaches to Inflammation in the Central Nervous System; Chapter 15 - Enhancing Epithelial Tissue Repair and Reducing Inflammation by Targeting Connexins; Back CoverPlasma membrane-associated channels known as gap junctions, along with their protein building blocks-connexins-have an important functional role in a range of immunological processes, including heart function, cell growth and specialization, and early development. Spanning basic science and potential clinical applications, Connexin Cell Communication Channels: Roles in the Immune System and Immunopathology assembles and synthesizes four decades of the most important research carried out in this field. The book first provides a historical overview of the discovery of these membrane channels in Gap junctions (Cell biology)ConnexinsInflammationGap junctions (Cell biology)Connexins.Inflammation.591.876041Oviedo-Orta Ernesto1683231Kwak Brenda R1683232Evans W. Howard531435MiAaPQMiAaPQMiAaPQBOOK9910827674403321Connexin cell communication channels4053886UNINA