03169nam 22006374a 450 991082758420332120200520144314.097866119390389781281939036128193903X9780470422465047042246797804704224580470422459(CKB)1000000000549814(EBL)380571(SSID)ssj0000131475(PQKBManifestationID)11134966(PQKBTitleCode)TC0000131475(PQKBWorkID)10026072(PQKB)11497513(Au-PeEL)EBL380571(CaPaEBR)ebr10263634(CaONFJC)MIL193903(FINmELB)ELB178309(MiAaPQ)EBC380571(OCoLC)299043648(Perlego)2755907(EXLCZ)99100000000054981420081021d2009 uy 0engur|n|---|||||txtccrCoupled bioluminescent assays methods, evaluations, and applications /Michael J. Corey1st ed.Hoboken, N.J. Wileyc20091 online resource (326 p.)Description based upon print version of record.9780470108833 0470108835 Includes bibliographical references (p. 265-289) and index.Introduction -- Coupled bioluminescent reactions in practice -- Coupled bioluminescent cytotoxicity assays -- The role of coupled bioluminescent assays in kinase screening and study -- Coupled bioluminescent phosphatase assays -- Acetylcholinesterase -- Measurement of nitric oxide synthase activity by coupled bioluminescence -- The coupled bioluminescent pyrophosphorolysis assay -- Coupled luminescent assays of G-protein-coupled receptors -- Coupled bioluminescent protease assays -- Coupled luminescent assays involving aequorin -- Coupled bioluminescent reporter assays -- Coupled bioluminescent assays : regulatory concerns -- Coupled bioluminescent determination of bioburden and sterility -- Environmental applications of coupled bioluminescent assays.This book highlights the applications of coupled bioluminescence assay techniques to real-world problems in drug discovery, environmental and chemical analysis, and biodefense. It separates theoretical aspects from the applied sections in a clear and readable way. Coupled Bioluminescent Assays, explains the uses of CB technologies across drug discovery to analyze toxicity, drug receptors, and enzymes. It covers applications in environmental analysis and biodefense, including cytotoxicity, fertilizer and explosives analysis, and nerve agent and pesticide detection. This is the premier referenceBioluminescence assayBioluminescence assay.612/.01442Corey Michael J(Michael James),1953-1622585MiAaPQMiAaPQMiAaPQBOOK9910827584203321Coupled bioluminescent assays3956524UNINA