05331nam 2200625Ia 450 991083079910332120230607213206.01-280-27011-X97866102701180-470-31452-40-470-85481-20-470-85482-0(CKB)111056485599104(EBL)141614(OCoLC)53831952(SSID)ssj0000215062(PQKBManifestationID)11201993(PQKBTitleCode)TC0000215062(PQKBWorkID)10167455(PQKB)11534882(MiAaPQ)EBC141614(EXLCZ)9911105648559910420020529d2002 uy 0engur|n|---|||||txtccrOn-line LC-NMR and related techniques[electronic resource] /edited by Klaus AlbertNew York J. Wiley & Sonsc20021 online resource (308 p.)Description based upon print version of record.0-471-49649-9 Includes bibliographical references and index.On-Line LC-NMR and Related Techniques; Contents; Contributors; Preface; 1 LC-NMR: Theory and Experiment; 1.1 Introduction; 1.2 NMR in a Flowing Liquid; 1.3 Design of Continuous-Flow NMR Probes; 1.4 Experimental Arrangement for HPLC-(1)H NMR Coupling; 1.5 Practical Considerations, Solvent Suppression Techniques, Gradient Elution and Purity of HPLC Solvents; 1.5.1 Solvent Signal Suppression; 1.5.2 Purity of HPLC-Grade Solvents; References; 2 LC-NMR: Automation; 2.1 Practical Use of LC-NMR and LC-NMR/MS; 2.2 Different Working Modes in LC-NMR; 2.2.1 On-Flow; 2.2.2 Direct Stop-Flow2.2.3 Loop Storage/Loop Transfer2.2.4 Conclusions; 2.3 Use of Mass Spectrometry in the Set-Up; 2.4 Measurement Procedures; 2.4.1 Sample Preparation and Introduction ('Injection') into the Chromatography System; 2.4.2 Chromatographic Separation; 2.4.3 Peak Detection and Selection; 2.4.4 Mass Spectrometric Measurements; 2.4.5 Nuclear Magnetic Resonance Measurements; 2.4.6 Sample Recovery; 2.5 Conclusions; References; 3 Biomedical and Pharmaceutical Applications of HPLC-NMR and HPLC-NMR-MS; 3.1 Introduction; 3.2 Technical and Operational Overview; 3.3 Applications in Combinatorial Chemistry3.4 Application to Chemical Impurities3.5 Application to Chiral Separations of Pharmaceutical Mixtures; 3.6 Application to Natural Products; 3.7 Application to Chemical Reactivity of Drug Glucuronides; 3.8 Application to Futile Deacetylation Reactions; 3.9 Application to Trapping of Reactive Intermediates; 3.10 Application to Uptake and Transformation of Xenobiotics by Plants; 3.11 Separation of Lipoproteins and their Characterisation using HPLC-NMR; 3.12 Superheated-Water HPLC-NMR and HPLC-NMR-MS Studies on Pharmaceuticals3.13 Application of Hypernation to a Mixture of Non-Steroidal Anti-Inflammatory Drugs3.14 Concluding Remarks; References; 4 Application of On-Line LC-NMR and Related Techniques to Drug Metabolism Studies; 4.1 Introduction; 4.2 LC-NMR Techniques; 4.2.1 Continuous-Flow LC-NMR; 4.2.2 Time-Slice LC-NMR; 4.2.3 Stop-Flow LC-NMR; 4.2.4 Loop-Storage; 4.2.5 LC-NMR-MS; 4.3 Application of LC-NMR-MS to Drug Metabolism: The Structure Elucidation of Rat Urinary Metabolites of Efavirenz by LC-NMR-MS; 4.3.1 Experimental; 4.3.2 Results; 4.4 Conclusions; References; 5 LC-NMR for Natural Products Analysis5.1 Application of LC-NMR and LC-NMR-MS Hyphenation to Natural Products Analysis5.1.1 Introduction; 5.1.1.1 General Aspects; 5.1.1.2 Applications; 5.1.2 Application of LC-NMR-MS to Glycosidic Natural Products of Marine Origin; 5.1.2.1 Introduction - Need for LC-NMR; 5.1.2.2 Methodology: On-Flow LC-NMR-MS Screening; 5.1.2.3 NMR - Structural Information; 5.1.2.4 Mass Spectrometry and D-H Back-Exchange Experiments; 5.1.2.5 Stop-Flow Experiments; 5.1.2.6 Complimentary Structural Information of NMR and MS; 5.1.2.7 Conclusions; 5.1.3 Acknowledgements; References5.2 Hyphenation of Modern Extraction Techniques to LC-NMR for the Analysis of Geometrical Carotenoid Isomers in Functional Food and Biological TissuesThis book gives a comprehensive overview of the basis and the current applications of LC-NMR and related techniques. It deals with the practical aspects of the hardware and software set-up for a successful performance of on-line coupling experiments. It covers the solution of real-word problems from the fields of biomedical, pharmaceutical and environmental studies as well as the analysis of natural products and polymeric compounds. Thus guidelines for an efficient application of the powerful hyphenated technique LC-NMR in combination with LC-MS are presented. Besides LC-NMR, important techniqNuclear magnetic resonance spectroscopyLiquid chromatographyNuclear magnetic resonance spectroscopy.Liquid chromatography.543.089543/.0877Albert Klaus1633043MiAaPQMiAaPQMiAaPQBOOK9910830799103321On-line LC-NMR and related techniques3972592UNINA05805nam 22007692 450 991082674220332120221214231533.01-107-45438-71-107-46144-81-139-89280-01-107-45937-01-107-47219-91-107-46512-51-107-46864-71-139-81468-0(CKB)2670000000433791(EBL)1543567(OCoLC)862077611(SSID)ssj0000999491(PQKBManifestationID)12336805(PQKBTitleCode)TC0000999491(PQKBWorkID)10933968(PQKB)10527871(UkCbUP)CR9781139814683(Au-PeEL)EBL1543567(CaPaEBR)ebr10795331(MiAaPQ)EBC1543567(EXLCZ)99267000000043379120121011d2013|||| uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierEncyclopaedism from antiquity to the Renaissance /editors, Jason König, Greg WoolfCambridge :Cambridge University Press,2013.1 online resource (xv, 601 pages) digital, PDF file(s)Title from publisher's bibliographic system (viewed on 05 Oct 2015).1-107-03823-5 Includes bibliographical references and index.1. Introduction: Jason Konig and Greg Woolf; Part I. Classical Encyclopaedism: 2. Encyclopaedism in the Roman Empire Jason Konig and Greg Woolf; 3. Encyclopaedism in the Alexandrian Library Myrto Hatzimichali; 4. Labores pro bono publico: the burdensome mission of Pliny's Natural History Mary Beagon; 5. Encyclopaedias of virtue? Collections of sayings and stories about wise men in Greek Teresa Morgan; 6. Plutarch's corpus of Quaestiones in the tradition of imperial Greek encyclopaedism Katerina Oikonomopoulou; 7. Artemidorus' Oneirocritica as fragmentary encyclopaedia Daniel Harris-McCoy; 8. Encyclopaedias and autocracy: Justinian's Encyclopaedia of Roman law Jill Harries; 9. Late Latin encyclopaedism: towards a new paradigm of practical knowledge Marco Formisano; Part II. Medieval Encyclopaedism: 10. Byzantine encyclopaedism of the ninth and tenth centuries Paul Magdalino; 11. The imperial systematisation of the past in Constantinople: Constantine VII and his Historical Excerpts Andres Nemeth; 12. Ad maiorem Dei gloriam: Joseph Rhakendys' synopsis of Byzantine learning Erika Gielen; 13. Shifting horizons: the medieval compilation of knowledge as mirror of a changing world Elizabeth Keen; 14. Isidore's Etymologies: on words and things Andrew Merrills; 15. Loose Giblets: encyclopaedic sensibilities of ordinatio and compilatio in later medieval English literary culture and the sad case of Reginald Pecock Ian Johnson; 16. Why was the fourteenth century a century of Arabic encyclopaedism? Elias Muhanna; 17. Opening up a world of knowledge: Mamluk encyclopaedias and their readers Maaike van Berkel; Part III. Renaissance Encyclopaedism: 18. Revisiting Renaissance encyclopaedism Ann Blair; 19. Philosophy and the Renaissance encyclopaedia: some observations D.C. Andersson; 20. Reading 'Pliny's Ape' in the Renaissance: the Polyhistor of Caius Julius Solinus in the first century of print Paul Dover; 21. Shakespeare's encyclopaedias Neil Rhodes; 22. Big dig: Dugdale's drainage and the dregs of England History of Embanking and Drayning Claire Preston; 23. Irony and encyclopedic writing before (and after) the Enlightenment William West; Part IV. Chinese Encyclopaedism: A Postscript: 24. The passion to collect, select, and protect: fifteen hundred years of the Chinese encyclopaedia Harriet Zurndorfer.There is a rich body of encyclopaedic writing which survives from the two millennia before the Enlightenment. This book sheds new light on that material. It traces the development of traditions of knowledge ordering which stretched back to Pliny and Varro and others in the classical world. It works with a broad concept of encyclopaedism, resisting the idea that there was any clear pre-modern genre of the 'encyclopaedia', and showing instead how the rhetoric and techniques of comprehensive compilation left their mark on a surprising range of texts. In the process it draws attention to both remarkable similarities and striking differences between conventions of encyclopaedic compilation in different periods, with a focus primarily on European/Mediterranean culture. The book covers classical, medieval (including Byzantine and Arabic) and Renaissance culture in turn, and combines chapters which survey whole periods with others focused closely on individual texts as case studies.Encyclopedias and dictionariesHistory and criticismEncyclopedistsLearning and scholarshipHistoryTo 1500Learning and scholarshipHistory16th centuryLearning and scholarshipHistory17th centuryCivilization, AncientCivilization, MedievalRenaissanceEncyclopedias and dictionariesHistory and criticism.Encyclopedists.Learning and scholarshipHistoryLearning and scholarshipHistoryLearning and scholarshipHistoryCivilization, Ancient.Civilization, Medieval.Renaissance.031.09König JasonWoolf GregUkCbUPUkCbUPBOOK9910826742203321Encyclopaedism from antiquity to the Renaissance3942783UNINA