03318nam 22006374a 450 991082556780332120200520144314.01-281-38211-697866113821170-470-37807-70-470-37778-X(CKB)1000000000535836(EBL)353476(OCoLC)437219605(SSID)ssj0000160512(PQKBManifestationID)11154741(PQKBTitleCode)TC0000160512(PQKBWorkID)10182114(PQKB)10683550(MiAaPQ)EBC353476(Au-PeEL)EBL353476(CaPaEBR)ebr10296375(CaONFJC)MIL138211(PPN)152319352(EXLCZ)99100000000053583620080125d2008 uy 0engurcn|||||||||txtccrGalectins /edited by Anatole A. Klyosov, Zbigniew J. Witczak, David Platt1st ed.Hoboken, N.J. John Wiley & Sonsc20081 online resource (302 p.)Description based upon print version of record.0-470-37318-0 Includes bibliographical references and index.GALECTINS; CONTENTS; Preface; Contributors; 1 Stumbling on Galectins; 2 Galectins and Their Functions in Plain Language; 3 Understanding Galectin Structure-Function Relationships to Design Effective Antagonists; 4 Galectins as Regulators of Tumor Growth and Invasion by Targeting Distinct Cell Surface Glycans and Implications for Drug Design; 5 Nuclear and Cytoplasmic Localization of Galectin-1 and Galectin-3 and Their Roles in Pre-mRNA Splicing; 6 Galectins in Regulation of Inflammation and Immunity7 Galectins as Danger Signals in Host-Pathogen and Host-Tumor Interactions: New Members of the Growing Group of ""Alarmins""?8 The Role of Galectins in Organ Fibrosis; 9 Galectin-1, Cancer Cell Migration, Angiogenesis, and Chemoresistance; 10 Galectin-3 in the Progression and Metastasis of Colorectal Neoplasia; 11 Galectins in Malignant Gliomas: Expression, Functions, and Possible Therapeutic Options; 12 Food-Related Carbohydrate Ligands for Galectins; IndexThe comprehensive guide to the current understanding of galectins and their promising potential in drug design This is the first book focusing on galectins. It was inspired by topics discussed at the symposium ""Galectins: Structures, Functions, and Therapeutic Targets"" that was a part of the 234th American Chemical Society meeting in 2007. To help chemists, biochemists, and others understand the challenges inherent in the study of galectins and build on recent advances in the field, the editors have compiled articles from leading experts on galectins and their biomedical applications.LectinsGalactoseLectins.Galactose.572/.69Klesov A. A(Anatolii Alekseevich)1604384Witczak Zbigniew J.1947-285729Platt David1953-1688013MiAaPQMiAaPQMiAaPQBOOK9910825567803321Galectins4061940UNINA