04535nam 22007214a 450 991082463580332120200520144314.0978661132011997812813201171281320110978047098481904709848139780470988473047098847997804709940920470994096(CKB)1000000000413718(EBL)351110(OCoLC)476170608(SSID)ssj0000147171(PQKBManifestationID)11146663(PQKBTitleCode)TC0000147171(PQKBWorkID)10010793(PQKB)10519793(MiAaPQ)EBC351110(Au-PeEL)EBL351110(CaPaEBR)ebr10236693(CaONFJC)MIL132011(Perlego)2758975(EXLCZ)99100000000041371820060621d2007 uy 0engur|n|---|||||txtccrEndothelial dysfunctions and vascular disease /edited by Raffaele De Caterina, Peter Libby ; foreword by Michael A. Gimbrone Jr1st ed.Malden, MA Blackwell Futura20071 online resource (432 p.)Description based upon print version of record.9781405122085 1405122080 Includes bibliographical references and index.Endothelial Dysfunctions and Vascular Disease; Contents; Contributors; Preface; Foreword; Acknowledgments; Dedication; Part I: The basis of endothelial involvement in vascular diseases; 1 Endothelial functions and dysfunctions; 2 Endothelial activation and the initiation of atherosclerosis; 3 Mechanisms of plaque progression and complications; 4 Angiogenesis in cardiovascular disease; Part II: The endothelium and cardiovascular risk factors; 5 VLDL and atherosclerosis; 6 High-density lipoprotein and atheroprotection7 Advanced glycation endproducts and the accelerated atherosclerosis in diabetes8 Homocysteine and endothelial dysfunction; 9 Lipoprotein(a) and the artery wall; 10 Oxidative stress and vascular disease; 11 Infections and vascular disease; Part III: Diagnostic tools and markers of endothelial functions; 12 Endothelial vasodilatory dysfunction: basic concepts and practical implementation; 13 Endothelial vasodilatory dysfunction and risk factors in adults; 14 Endothelial vasodilatory dysfunction in early life; 15 Endothelial vasodilatory dysfunction in hypertension16 Vascular function and diabetes mellitus17 Dyslipidemia and endothelial dysfunction: pathophysiology and therapy; 18 Soluble adhesion molecules as in vivo biohumoral markers of vascular cell activation; Part IV: Endothelium-directed prevention and therapy; 19 Hormone replacement therapy and cardiovascular disease; 20 Anti-atherogenic effects of omega-3 fatty acids; 21 Treatment of endothelial dysfunction and atherosclerosis by cholesterol lowering; 22 Antioxidants and endothelial protection23 Angiotensin-converting enzyme inhibitors and angiotensin II type 1 receptor blockers to reverse endothelial dysfunction24 PPARs in atherosclerosis; 25 Stem cells in atherosclerosis and atherosclerosisrelated vascular disorders; 26 Endothelium-targeted gene and cell-based therapy for cardiovascular disease; IndexBridging the gap between the laboratory and the bedside, this timely volume illuminates the connection between endothelial dysfunction and vascular disease. This comprehensive survey of atherosclerotic disease begins with biology - incorporating the latest breakthroughs in the field - then elucidates risk factors and diagnostic tools and markers. A major section on endothelium-directed prevention and therapy shows you how to apply cutting-edge research to clinical care. Under the careful editorial guidance of Drs. De Caterina and Libby, the highly-regarded contributors address:- endothelBlood-vesselsPathophysiologyVascular endotheliumBlood-vesselsPathophysiology.Vascular endothelium.616.1/3De Caterina R.1954-602130Libby Peter750680MiAaPQMiAaPQMiAaPQBOOK9910824635803321Endothelial dysfunctions and vascular disease2189336UNINA