04106nam 2200649 a 450 991082338750332120200520144314.01-281-23744-297866112374480-470-25344-40-470-25342-8(CKB)1000000000406149(EBL)333730(SSID)ssj0000111881(PQKBManifestationID)11128802(PQKBTitleCode)TC0000111881(PQKBWorkID)10080565(PQKB)10262835(Au-PeEL)EBL333730(CaPaEBR)ebr10226758(CaONFJC)MIL123744(OCoLC)214281384(MiAaPQ)EBC333730(EXLCZ)99100000000040614920070820d2008 uy 0engur|n|---|||||txtccrBioinformatics algorithms techniques and applications /edited by Ion I. Mandoiu and Alexander Zelikovsky1st ed.Hoboken, N.J. Wiley-Intersciencec20081 online resource (517 p.)Wiley series on bioinformaticsDescription based upon print version of record.0-470-09773-6 Includes bibliographical references and index.BIOINFORMATICS ALGORITHMS; CONTENTS; Preface; Contributors; 1 Educating Biologists in the 21st Century: Bioinformatics Scientists versus Bioinformatics Technicians; PART I TECHNIQUES; 2 Dynamic Programming Algorithms for Biological Sequence and Structure Comparison; 3 Graph Theoretical Approaches to Delineate Dynamics of Biological Processes; 4 Advances in Hidden Markov Models for Sequence Annotation; 5 Sorting- and FFT-Based Techniques in the Discovery of Biopatterns; 6 A Survey of Seeding for Sequence Alignment; 7 The Comparison of Phylogenetic Networks: Algorithms and ComplexityPART II GENOME AND SEQUENCE ANALYSIS8 Formal Models of Gene Clusters; 9 Integer Linear Programming Techniques for Discovering Approximate Gene Clusters; 10 Efficient Combinatorial Algorithms for DNA Sequence Processing; 11 Algorithms for Multiplex PCR Primer Set Selection with Amplification Length Constraints; 12 Recent Developments in Alignment and Motif Finding for Sequences and Networks; PART III MICROARRAY DESIGN AND DATA ANALYSIS; 13 Algorithms for Oligonucleotide Microarray Layout; 14 Classification Accuracy Based Microarray Missing Value Imputation; 15 Meta-Analysis of Microarray DataPART IV GENETIC VARIATION ANALYSIS16 Phasing Genotypes Using a Hidden Markov Model; 17 Analytical and Algorithmic Methods for Haplotype Frequency Inference: What Do They Tell Us?; 18 Optimization Methods for Genotype Data Analysis in Epidemiological Studies; PART V STRUCTURAL AND SYSTEMS BIOLOGY; 19 Topological Indices in Combinatorial Chemistry; 20 Efficient Algorithms for Structural Recall in Databases; 21 Computational Approaches to Predict Protein-Protein and Domain-Domain Interactions; IndexPresents algorithmic techniques for solving problems in bioinformatics, including applications that shed new light on molecular biology This book introduces algorithmic techniques in bioinformatics, emphasizing their application to solving novel problems in post-genomic molecular biology. Beginning with a thought-provoking discussion on the role of algorithms in twenty-first-century bioinformatics education, Bioinformatics Algorithms covers: General algorithmic techniques, including dynamic programming, graph-theoretical methods, hidden Markov models, the fast Fourier transform, seWiley series on bioinformatics.BioinformaticsAlgorithmsBioinformatics.Algorithms.572.80285Mandoiu Ion856333Zelikovsky Alexander919949MiAaPQMiAaPQMiAaPQBOOK9910823387503321Bioinformatics algorithms4090751UNINA