07061nam 2200637Ia 450 991082337400332120200520144314.01-280-73558-997866107355871-84593-090-89780851990804(CKB)1000000000344575(OCoLC)228146904(CaPaEBR)ebrary10157965(SSID)ssj0000173042(PQKBManifestationID)11180011(PQKBTitleCode)TC0000173042(PQKBWorkID)10161782(PQKB)10845833(MiAaPQ)EBC289432(Au-PeEL)EBL289432(CaPaEBR)ebr10157965(CaONFJC)MIL73558(EXLCZ)99100000000034457520050228d2005 uy 0engurcn|||||||||txtccrHormonal regulation of farm animal growth /K.L. Hossner1st ed.Wallingford, Oxfordshire, UK ;Cambridge, MA CABI Pub.c20051 online resource (231 p.) Bibliographic Level Mode of Issuance: Monograph0-85199-080-0 Includes bibliographical references and index.Intro -- Contents -- 1 Whole Animal Growth -- Measuring Animal Growth -- Embryonic and Fetal Growth -- Growth Curves -- Genetics, Nutrition and Environmental Effects on Whole Animal Growth -- Genetics -- Nutrition -- Environmental factors -- 2 Cellular and Molecular Biology -- Prokaryotic and Eukaryotic Organisms -- Eukaryotic cell organelles -- The Cell Cycle -- The Central Dogma of Cell Biology -- Eukaryotic genes -- Ribonucleic Acid -- Messenger RNA and translation of protein -- RNA polymerases -- Regulation of gene transcription -- Transcriptional control of specific genes -- Transcription factors -- Biotechnology and Genetic Engineering -- Transgenic Animals and their Potential -- Identifying, Isolating and Transferring Genes -- Homologous recombination, gene targeting and gene knockouts -- 3 The Endocrine System -- Control of Pituitary Hormone Secretion -- Hormone Receptors -- Effector Molecules, Transducers and Second Messengers -- 4 Development of Muscle, Skeletal System and Adipose Tissue -- Embryonic Development and Cell Differentiation -- Cell Proliferation and Differentiation -- The Skeletal System and Bone Growth -- Types of Bones and Gross Anatomy -- Bone Cells and Bone Matrix Formation -- Osteoclasts and bone resorption -- Regulation of osteoclast function -- The Epiphyseal Plate -- Skeletal Muscle Development -- Embryonic formation of skeletal muscle -- Skeletal muscle satellite cells -- Myofilaments, Myofibrils and Sarcomeres -- Sarcomeric proteins: actin, myosin and titin -- Myofibres and muscle contraction -- Skeletal Muscle Fibre Types -- Skeletal muscle protein turnover -- The formation of multinucleated skeletal muscle cells -- Adipose Tissue Growth and Development -- Brown adipose tissue -- White adipose tissue -- Adipose tissue development -- Adipose tissue growth: hyperplasia vs hypertrophy -- Lipogenesis and Lipolysis.5 Growth Hormone and Insulin-like Growth Factors -- The GH Molecule -- Control of GH secretion -- GH receptors -- Metabolic actions of GH -- Excess and inadequate GH: giants and dwarfs -- IGFs or Somatomedins -- Discovery of the IGFs -- IGF genes and molecules -- IGF receptors -- IGF-binding proteins -- Metabolic effects of the IGFs -- Effects of the IGFs on animal growth -- Modification of the somatomedin hypothesis -- Effects of GH on Farm Animal Production -- GH and the development of transgenic animals -- 6 Calcium Homeostasis and Regulation of Bone Growth -- Hormonal Regulation of Calcium Homeostasis -- Parathyroid hormone -- 1,25-Dihydroxy vitamin D[sub(3)] -- Biological actions of 1,25-dihydroxy vitamin D[sub(3)] -- Calcitonin -- Regulation of Bone Growth and Development -- The hedgehogs and early skeletal differentiation -- Regulation of bone growth and differentiation by hormones -- Growth factors and bone -- FGF -- PDGF -- Transforming growth factor-&amp -- #946 -- -- Bone morphogenetic proteins -- 7 Hormones, Growth Factors and Skeletal Muscle -- Experimental Systems to Study Myogenesis -- Myogenic cell systems -- Muscle Regulatory Factors (MRFs) -- Effects of the MRFs on muscle development -- Regulation of MRF expression -- Growth Factors Affecting Muscle Growth -- IGFs -- Myostatin -- FGF -- TGF-&amp -- #946 -- -- BMPs -- Hepatocyte growth factor -- Hormones regulating muscle growth -- 8 Hormones, Growth Factors and Adipose Tissue -- Cell Systems Used to Study Adipogenesis -- Transcription Factors and Adipogenesis -- PPARs -- C/EBPs -- ADD1/SREBP1 -- Nuclear co-activators and co-repressors: fine-tuning the adipogenic response -- Hormones and Growth Factors Affecting Preadipocytes and Adipocytes -- Insulin -- GH and the IGFs -- Glucocorticoids -- Prostaglandins and cAMP -- Negative Regulators of Adipose Differentiation.Adipose tissue as an endocrine organ -- 9 Steroids and Animal Growth -- Oestrogens and Ruminant Growth -- Oestrogens and Non-ruminants -- Androgens and Ruminant Growth -- Mechanism of Action of Steroids in Ruminant Growth -- Androgen mechanisms of action -- 10 Catecholamines, Beta-agonists and Nutrient Repartitioning -- The Autonomic Nervous System and the Adrenal Medulla -- Adrenergic Receptors -- &amp -- #946 -- -Adrenergic agonists -- Effects of &amp -- #946 -- -adrenergic agonists on growth and body composition -- 11 Leptin, Body Composition and Appetite Control -- Theories on the Short-term Regulation of Food Intake -- The Long-term Regulation of Food Intake - the Lipostat Theory -- The Discovery of Leptin -- The leptin gene and molecule -- Leptin receptors and binding proteins -- Biological actions of leptin -- Effects of leptin on reproduction -- Direct peripheral effects of leptin -- Regulation of leptin concentrations -- Significance of leptin to animal production -- Appetite-inducing (Orexigenic) Peptides of the Hypothalamus -- Index -- A -- B -- C -- D -- E -- F -- G -- H -- I -- J -- K -- L -- M -- N -- O -- P -- Q -- R -- S -- T -- U -- V -- W -- Z.This book describes the cellular and molecular mechanisms that are involved with the regulation of cell and tissue growth, including development and body composition. The emphasis is on circulating hormones, local growth factors and gene transcription factors which regulate growth and differentiation of skeletal muscle, bone and adipose tissue.Growth regulatorsHormonesLivestockGrowthRegulationGrowth regulators.Hormones.LivestockGrowthRegulation.636.08/52Hossner K. L(Kim L.)523481MiAaPQMiAaPQMiAaPQBOOK9910823374003321Hormonal regulation of farm animal growth830013UNINA