05815nam 2200709 450 991082262970332120230803222448.01-118-84701-61-118-84694-X1-118-84723-7(CKB)2560000000148553(EBL)1676381(SSID)ssj0001181778(PQKBManifestationID)11634854(PQKBTitleCode)TC0001181778(PQKBWorkID)11146171(PQKB)10398450(OCoLC)869847755(MiAaPQ)EBC1676381(DLC) 2014003283(Au-PeEL)EBL1676381(CaPaEBR)ebr10862633(CaONFJC)MIL599913(OCoLC)877771918(EXLCZ)99256000000014855320140506h20142014 uy 0engur|n|---|||||txtccrRibosome-inactivating proteins ricin and related proteins /edited by Fiorenzo Stirpe, Douglas A. LappiAmes, Iowa ;Chichester, England ;Oxford, England :Wiley,2014.©20141 online resource (326 p.)Description based upon print version of record.1-306-68662-8 1-118-12565-7 Includes bibliographical references at the end of each chapters and index.Ribosome-inactivating Proteins: Ricin and Related Proteins; Copyright; Contents; Contributors; Preface; 1 Introduction and History; Introduction; Identification and Distribution in Nature; Mechanism of Action; Effects on Cells and Animals; Role in Nature; Practical Applications; In Agriculture; In Medicine; Bioweapons; Future Challenges; References; 2 Occurrence and Taxonomical Distribution of Ribosome-inactivating Proteins Belonging to the Ricin/Shiga Toxin Superfamily; Introduction; How to Investigate the Distribution of Proteins with an N-glycosidase Domain?Overview of the Occurrence of the N-glycosidase Domain in Living OrganismsPlant RIPs; Bacterial RIPs - Shiga Toxin Group; Distantly Related Non-secreted Protein Homolog of Stx A Subunit; RIPs in Actinobacteria; Fungal RIPs; Insect RIPs; Conclusions; Acknowledgments; References; 3 Ribosome-inactivating Proteins from Phytolaccaceae; Introduction; Physicochemical Properties and Structure; Enzymatic Activities of RIPs from Phytolaccaceae; Biological Activity; 4 Ribosome-inactivating Proteins in Caryophyllaceae, Cucurbitaceae, and Euphorbiaceae; Introduction; Caryophyllaceae RIPs; AgrostinDianthinGypsophilin; Petroglaucin 1 and Petrograndin; Saporin; RIPs from Saponaria Ocymoides and Vaccaria Pyramidata; Cucurbitaceae RIPs; Bryodin; Colocin 1 and Colocin 2; Cucumis Melo; Cucurmosin; Hispin; Lagenin; Luffangulin; Luffa Cylindrica Protein Synthesis Inhibitors; Luffin; Luffacylin (Small RIP); LuffinS (Small RIP); Luffin P1 (Small RIP); Balsamin; Bitter Gourd Protein (MRK29); MAP30; Alpha- and Beta-Momorcharins; Charantin (Small RIP); Momorcochin; Cochinin B; Momorgrosvin; MOR-I and MOR-II; Moschatin; Cucurbita Moschata RIP; Pepocin; Sechiumin; Trichoanguin; TrichobitacinTrichokirinTrichokirin-S1 (Small RIP); Trichomaglin; Trichosanthin; Karasurin-A, Karasurin-B, and Karasurin-C; Trichosanthrip (Small RIP); Euphorbiaceae RIPs; Croton Tiglium and Jatropha Curcas Protein Synthesis Inhibitors; Curcin; Gelonin; Lychnin; Mapalmin; Type 1 RIPs from other Families; Amaranthin (Family Amaranthaceae); Basella Rubra RIPs (Family Basellaceae) and Bougainvillea Spectabilis RIP (Family Nyctaginaceae); Beta Vulgaris RIP (Family Chamnopodiaceae); Nigritins f1 and f2 (Family Caprifoliaceae); Charybdin (Family Hyacinthaceae); Iris RIP (Family Iridaceae)Camphorin (Family Lauraceae)Mirabilis Jalapa RIP (Family Nyctaginaceae); Barley (Family Poaceae); Wheat (Family Poaceae); Algal RIPs; Lamjapin (Family Laminariaceae); Fungal RIPs; Clavin (Family Trichocomaceae); Flammin and Velin (Family Tricholomataceae); Flammulin (Family Tricholomataceae); Hypsin (Family Tricholomataceae); Lyophyllin (Family Tricholomataceae); Marmorin (Family Tricholomataceae); Pleuturegin (Family Pleurotaceae); Velutin (Family Tricholomataceae); Volvarin (Family Plutaceae); Crystal Structures of RIPs; Production of Recombinant RIPs; Immunoreactivity of RIPsEffects of Thiolation on the Immunoreactivity of the RIP gelonin"This important reference provides up-to-date information on all aspects of ribosome-inactivating proteins (RIPs). Including a list of all known RIPs, their distribution in nature, structure, genetics and chemical and immunological properties, this reference covers mechanisms of action, including the enzymatic activity on various polynucleotide substrates; the interaction with, and entry into cells; the toxicity to animals, including the pathology of poisoning; and the immunomodulatory and allergenic activity. The book further emphasizes the use of immunotoxins and other conjugates in clinical trials for the therapy of cancer and intractable pain"--Provided by publisher."Ribosome-inactivating Proteins is a reference book which will provide up-to-date information on all aspects of ribosome-inactivating proteins (RIPs)"--Provided by publisher.ProteinsSynthesisRibosomesStructureProteinsSynthesis.RibosomesStructure.571.6/58SCI017000bisacshLappi Douglas A.Stirpe FiorenzoMiAaPQMiAaPQMiAaPQBOOK9910822629703321Ribosome-inactivating proteins4017440UNINA