04888nam 2200661 450 991082147000332120200520144314.01-78242-087-81-78242-095-9(CKB)3710000000499536(EBL)4082037(SSID)ssj0001586796(PQKBManifestationID)16269761(PQKBTitleCode)TC0001586796(PQKBWorkID)14869387(PQKB)10869599(Au-PeEL)EBL4082037(CaPaEBR)ebr11117796(CaONFJC)MIL847040(OCoLC)927969318(MiAaPQ)EBC4082037(EXLCZ)99371000000049953620151123h20162016 uy 0engur|n|---|||||txtccrCharacterisation and design of tissue scaffolds /edited by Paul Tomlins ; contributors, S. F. Badylak [and twenty others]Amsterdam, [Netherlands] :Woodhead Publishing,2016.©20161 online resource (296 p.)Woodhead Publishing Series in Biomaterials ;Number 106Description based upon print version of record.Includes bibliographical references at the end of each chapters and index.""Front Cover""; ""Characterisation and Design of Tissue Scaffolds""; ""Copyright Page""; ""Contents""; ""List of contributors""; ""Woodhead publishing series in biomaterials""; ""1 Material types for tissue scaffolds""; ""Introduction""; ""Polymers""; ""Naturally occurring polymers""; ""Polysaccharides""; ""Alginates""; ""Chitosan""; ""Xanthan""; ""Proteins""; ""Collagen""; ""Fibrin and fibrinogen""; ""Hyaluronic acid""; ""Synthetic polymers""; ""Polyesters""; ""Polyethers""; ""Synthetic proteins""; ""Ceramics""; ""De-cellularized matrices""; ""Characterization of materials""""Sterilization""""Future trends""; ""Sources of further information""; ""References""; ""2 Designing and modeling pore size distribution in tissue scaffolds""; ""Background""; ""Modeling of pore architecture and its effect on the process of tissue engineering""; ""Selection of fabrication technique in terms of pore size distribution-with emphasis on polymer-based scaffolds""; ""Electrospinning of tissue engineered vascular grafts-the effect of pore morphology on the mechanical and biological functio...""; ""Conclusion""; ""References""""3 Computer modeling of the degradation behavior of polyester-based tissue engineering scaffolds""""Introduction""; ""Tissue engineering scaffolds""; ""Factors controlling the degradation rate of scaffolds""; ""Material factors""; ""The effect of geometry""; ""Environmental conditions""; ""A mathematical model for the degradation of bioresorbable polyesters""; ""Degradation maps""; ""Computer modeling of scaffold degradation using finite element methods""; ""FE modeling procedure""; ""Foamlike scaffolds""; ""Size effect zone""; ""Molecular weight""; ""Scission rate""""Short chain diffusion""""Fibrous scaffolds""; ""Size effect zone""; ""Molecular weight""; ""Scission rate""; ""Short chain diffusion""; ""Conclusion""; ""References""; ""4 Decellularization of mammalian tissues: preparing extracellular matrix bioscaffolds""; ""Introduction""; ""Rationale and relevance for clinical use of decellularized tissues""; ""Establishing a criteria for decellularization efficacy""; ""Decellularization agents""; ""Hypertonic and hypotonic solutions""; ""Acids and alkaline bases""; ""Acids""; ""Alkaline bases""; ""Detergents""; ""Nonionic detergents""""Ionic detergents""""Zwitterionic detergents""; ""Solvents""; ""Tri(n-butyl)phosphate""; ""Alcohols""; ""Biological agents""; ""Enzymes""; ""Nonenzymatic biologic agents""; ""Chelating agents""; ""Toxins""; ""Decellularization techniques""; ""Immersion and agitation""; ""Use of pressure as a decellularization technique""; ""Supercritical fluid""; ""Perfusion decellularization of whole organ constructs""; ""Terminal sterilization of decellularized tissues""; ""Decellularization agents that act as disinfectants""; ""Depyrogenation""; ""Ionizing radiation""; ""Ethylene oxide exposure""""Conclusion""Woodhead Publishing series in biomaterials ;Number 106.Tissue engineeringMaterialsTissue scaffoldsBiomedical materialsTissue engineeringMaterials.Tissue scaffolds.Biomedical materials.610.284Tomlins PaulBadylak S. F.MiAaPQMiAaPQMiAaPQBOOK9910821470003321Characterisation and design of tissue scaffolds4083837UNINA