04120nam 22007093u 450 991082076960332120240516202759.01-118-35818-X1-283-54246-397866138549191-118-35817-11-118-35751-51-118-35819-8(CKB)2550000000105052(EBL)965078(OCoLC)799766415(SSID)ssj0000686912(PQKBManifestationID)11426320(PQKBTitleCode)TC0000686912(PQKBWorkID)10735254(PQKB)11567971(MiAaPQ)EBC965078(EXLCZ)99255000000010505220131111d2012|||| u|| |engurcnu||||||||txtccrAmino Acid Metabolism3rd ed.Hoboken Wiley20121 online resource (480 p.)Description based upon print version of record.0-470-66151-8 1.4.1 Purine synthesis 1.4.1.1 Phosphoribosyl pyrophosphate (PRPP) synthetase; 1.4.1.2 PRPP amidotransferase; 1.4.2 Purine catabolism and salvage; 1.4.2.1 Adenosine deaminase deficiency - severe combined immune deficiency; 1.4.2.2 Gout and hyperuricaemia; 1.4.2.3 HGPRT deficiency - the Lesch-Nyhan syndrome; 1.4.3 Pyrimidine synthesis; 1.4.3.1 Orotic aciduria; 1.4.4 Pyrimidine catabolism and salvage; 1.5 Deamination of amino acids; 1.5.1 Amino acid oxidases; 1.5.2 Amine oxidases; 1.5.3 Glutamate and alanine dehydrogenases; 1.5.4 Non-oxidative deamination of amino acids1.5.5 Glutaminase and asparaginase 1.6 Excretion of nitrogenous waste; 1.6.1 Uricotelic and purinotelic species; 1.6.2 Ureotelic species; 1.6.2.1 Urea synthesis; 1.6.2.2 Inborn errors of metabolism affecting the urea synthesis cycle; 1.6.2.3 Entero-hepatic circulation of urea; 1.6.2.4 Canavanine; 1.7 Other nitrogenous compounds in human urine; 1.7.1 Aminoacidurias; Further reading; 2: Nitrogen Balance and Protein Turnover - Protein and Amino Acids in Human Nutrition; 2.1 Nitrogen balance and protein requirements; 2.1.1 Protein digestion and absorption2.1.2 Protein digestibility and unavailable amino acids in dietary proteins 2.1.3 Obligatory nitrogen losses; 2.1.4 Dynamic equilibrium and tissue protein turnover; 2.1.5 Tissue protein catabolism; 2.1.5.1 Lysosomal autophagy; 2.1.5.2 Ubiquitin and the proteasome; 2.1.5.3 Active site proteolysis of apo-enzymes; 2.1.6 Whole body protein turnover; 2.1.6.1 The constant infusion, labelled precursor method; 2.1.6.2 The constant infusion, labelled end product method; 2.1.6.3 Rates of whole-body protein turnover; 2.1.6.4 The catabolic drive and amino acid oxidation2.1.6.5 The energy cost of protein turnoverAmino Acid Metabolism, 3rd Edition covers all aspects of the biochemistry and nutritional biochemistry of the amino acids. Starting with an overview of nitrogen fixation and the incorporation of inorganic nitrogen into amino acids, the book then details other major nitrogenous compounds in micro-organisms, plants and animals. Contents include a discussion of the catabolism of amino acids and other nitrogenous compounds in animals, and the microbiological reactions involved in release of nitrogen gas back into the atmosphere. Mammalian (mainly human) protein and amino acidAmino acidsMetabolismAmino Acids, Peptides, and ProteinsMetabolic PhenomenaDrugsMetabolismAmino AcidsAmino acidsMetabolismAmino Acids, Peptides, and ProteinsMetabolic PhenomenaDrugsMetabolismAmino Acids572.65572/.65Bender David A321362AU-PeELAU-PeELAU-PeELBOOK9910820769603321Amino acid metabolism809162UNINA