03401nam 2200457 450 991081987890332120230627032545.090-8974-993-4(CKB)4900000000569146(MiAaPQ)EBC7217669(Au-PeEL)EBL7217669(OCoLC)1373983925(EXLCZ)99490000000056914620230627d2022 uy 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierRestorative justice from a children's rights perspective /edited by Annemieke Wolthuis and Tim Chapman1st ed.The Hague, Netherlands :Eleven,[2022]©20221 online resource (342 pages)94-6236-227-0 Intro -- About the series -- Acknowledgments -- Beyond rhetoric on children's rights and restorative justice -- Table of Contents -- Introduction -- Part I International standards and reflections on restorative justice for children -- Chapter 1 Restorative justice, a child's right -- Chapter 2 Restorative practices can steal the rights of children too - The importance of value-led and evidence-based standards -- Chapter 3 The UN Committee on the Rights of the Child - How we work and what child victims and offenders need -- Chapter 4 Child victims and child perpetrators in restorative justice - A Needs-Rights Model -- Chapter 5 Rights-based restorative justice - Questioning and decolonizing our ways of knowing, doing and being in Canada and beyond -- Part II Global developments &amp -- trends of restorative justice for children -- Chapter 6 Restorative justice for children around the globe - International perspectives and trends -- Chapter 7 Restorative justice in European youth justice systems - Contextual, legal, practice-related and analytical aspects -- Chapter 8 Restorative child justice: South Africa, Namibia and Zimbabwe -- Part III Local practices and challenges for restorative justice approaches with children -- Chapter 9 Introducing restorative practices in the child justice system of Georgia -- Chapter 10 Restorative justice and children's rights in Aotearoa New Zealand - Convergence and divergence -- Chapter 11 The potential of restorative justice to fulfill the children's right to be heard - The experience in Chile -- Chapter 12 When child-friendly justice meets restorative justice in a welfare model - The case of France -- Chapter 13 Restorative justice for young people in Poland - The law, current practices and prospects for improvement.Chapter 14 Child justice in the Netherlands - A boost for restorative and child-friendly interventions? -- Chapter 15 Rights, restoration and justice for children - Shaking the Movers in Canada -- Chapter 16 Strengthening rights and participation of children - A Finnish perspective on a restorative approach to education.Children's rightsRestorative justiceChildren's rights.Restorative justice.362.88083Wolthuis AnnemiekeChapman Tim1964-MiAaPQMiAaPQMiAaPQBOOK9910819878903321Restorative justice from a children's rights perspective3970949UNINA05428nam 2200673Ia 450 991083045110332120230828230856.01-282-30244-297866123024423-527-61194-03-527-60870-2(CKB)1000000000687512(EBL)481286(OCoLC)468787369(SSID)ssj0000343201(PQKBManifestationID)11255581(PQKBTitleCode)TC0000343201(PQKBWorkID)10289226(PQKB)10946255(MiAaPQ)EBC481286(EXLCZ)99100000000068751220050629d2006 uy 0engur|n|---|||||txtccrStandards of mouse model phenotyping[electronic resource] /edited by Martin Hrabede Angelis, Pierre Chambon, and Steve BrownWeinheim Wiley-VCHc20061 online resource (359 p.)Description based upon print version of record.3-527-31031-2 Includes bibliographical references and index.Standards of Mouse Model Phenotyping; Foreword; Table of Contents; Preface; 1 Characterizing Hearing in Mice; 1.1 Introduction; 1.2 Behavioral Tests of Hearing; 1.3 Physiological Tests of Hearing; 1.4 Anatomy of the Ear; 1.5 Conclusions; Acknowledgements; 2 Molecular Phenotyping: Gene Expression Profiling; 2.1 Why this Screen? Medical and Biological Relevance; 2.2 Examples: Diseases of Mouse and Man; 2.3 Diagnostic Methods: History and State of the Art; 2.4 Technical Requirements for Screening Protocols (Short): First and Second Line Approaches; 2.5 Logistics (Whom, When, How Many, Why)2.5.1 Choice of Platform2.5.2 Biological Samples; 2.6 Trouble Shooting; 2.6.1 Preparation of Hybridization Target; 2.6.2 Critical Issues of Chip Hybridization; 2.6.3 Image Processing and Array Design; 2.7 Short-term Outlook; 3 Screening for Bone and Cartilage Phenotypes in Mice; 3.1 Introduction; 3.1.1 The Skeleton; 3.1.2 Skeletal Development in the Embryo; 3.1.3 Growth and Maintenance of Bone and Cartilage; 3.1.4 Diseases Involving Cartilage and Bone; 3.1.5 The Mouse as a Model for Skeletal Diseases; 3.2 Screening Protocols; 3.2.1 Morphological Analysis; 3.2.1.1 Protocol3.2.2 X-Ray Analysis3.2.2.1 General; 3.2.2.2 Imaging; 3.2.2.3 X-Ray Analysis; 3.2.2.4 Protocol; 3.2.3 DXA-Analysis; 3.2.3.1 General; 3.2.3.2 Advantages; 3.2.3.3 Disadvantages; 3.2.3.4 Small Animal Applications; 3.2.3.5 Precision and Accuracy; 3.2.3.6 Considerations; 3.2.3.7 Protocol; 3.2.4 Biochemical Bone Markers; 3.2.4.1 Clinical Utility of Biochemical Markers of Bone Turnover in Small Animals; 3.2.4.2 Mouse Markers of Bone Turnover/Metabolism and Hormonal Regulation; 3.2.4.3 Variability/Sensitivity/Sample Choice; 3.2.4.4 Which Markers Should be Used During the Screen?3.2.5 Advanced Small Animal Imaging Techniques3.2.5.1 pQCT; 3.2.5.2 μCT; 3.2.5.3 μMRI; 3.2.5.4 Whole-mount Skeletal Preparations; 3.2.5.5 Histomorphometry; 3.2.5.6 Miscellaneous; 3.2.5.7 Order of the Tests; 3.3 Conclusion; List of Abbreviations; Appendix; μCT Volumetric Data Processing; MRI Principles; 4 Clinical Chemical Screen; 4.1 Introduction; 4.1.1 Relevance of the Screen; 4.1.2 Biology and Medical Application; 4.1.2.1 Biology of Clinical Chemical Parameters; 4.1.2.2 Medical Application; 4.2 Diseases in Mouse and Humans; 4.2.1 Diagnostic Impact of Clinical Chemistry4.2.2 Clinical Chemistry in Selected Disorders4.2.2.1 Hypercholesterolemia; 4.2.2.2 Albuminuria; 4.2.2.3 Acute Myeloid Leukemia (AML); 4.3 Clinical Chemistry as Diagnostic Tool; 4.3.1 History; 4.3.2 State of the Art; 4.4 Technical Requirements and Screening Protocols; 4.4.1 Technical Requirements; 4.4.1.1 Blood Collection; 4.4.1.2 Sample Preparation; 4.4.1.3 Sample Analysis; 4.4.2 Screening Protocols; 4.4.2.1 Primary Screen; 4.4.2.2 Secondary Screen; 4.4.2.3 Tertiary Screen; 4.5 Logistics of the Screen; 4.5.1 General Considerations; 4.5.2 Lessons from ENU Mutants; 4.6 Trouble Shooting4.6.1 Factors Interfering In VivoThis is the first book in the field of mouse genetics to provide comprehensive and standardized methods for the characterization of laboratory mice. The editor is Director of the German Mouse Clinic and member of the Project Committee of the German National Genome Research Network and provides here a brief introduction to the mouse as a model for diseases and functional analysis of genes and proteins. Throughout, he focuses on the characterization of mouse models using the latest phenotyping methods, with the different areas presented in a clearly structured and easily accessible manner.Mice as laboratory animalsMiceGeneticsTransgenic micePhenotypeMice as laboratory animals.MiceGenetics.Transgenic mice.Phenotype.599.353135Hrabé de Angelis Martin1621348Chambon Pierre1621349Brown Stephen D. M92951MiAaPQMiAaPQMiAaPQBOOK9910830451103321Standards of mouse model phenotyping3954587UNINA