03461oam 2200505 450 991013709870332120230807212008.0(CKB)3710000000824702(oapen)https://directory.doabooks.org/handle/20.500.12854/43471(EXLCZ)99371000000082470220160822h20152015 fy 0engurmn#---|||||txtrdacontentcrdamediacrrdacarrierCognitive deficits in schizophrenia and other neuropsychiatric disorders[electronic resource] convergence of preclinical and clinical evidence /edited by Ales Stuchlik and Tomiki SumiyoshiFrontiers Media SA2015Lausanne, Switzerland :Frontiers Media SA,2015.©20151 online resource (283 pages) illustrations, charts; digital, PDF file(s)Frontiers research topicsPublished in Frontiers in Behavioral Neuroscience.2-88919-679-8 Includes bibliographical references.Neuropsychiatric disorders such as schizophrenia, extrapyramidal disorders, Alzheimer's disease and other unrelated dementias, represent a serious human, medical and socioeconomic burden. These diseases are often accompanied by impairments of cognitive function, e.g., thinking, decision-making, and learning and memory. Such deficits significantly worsen quality of life and daily functioning of afflicted patients. Cognitive deficits in schizophrenia and other psychiatric diseases are associated with alterations of brain morphology and function, which are often resistant to therapeutic interventions. In schizophrenia and related disorders, cognitive deficits are also defined as endophenotypes, measurable phenotypes linking these complex disorders with discrete heritable and reproducible traits. This points to the importance of elucidating these endophenotypes in translational studies. Experimental animal models may not mimic the full spectrum of clinical symptoms, but may work as analogies of particular behaviors or other disease manifestations. They are useful to search for the etiology of particular psychiatric illnesses and novel therapeutics. Moreover, there is accumulated evidence showing (sometimes highly specific) deficits in cognition in these animal models of neuropsychiatric disorders. Moreover, there are a series of sensitive tests to measure cognitive performance in rodents and other species. The primary focus of the present topic is to provide up-to-date information on cognitive deficits of central nervous system (CNS) disorders, and delineate future directions for translational studies aimed at developing novel treatments/interventions of these disturbances, both at clinical and preclinical levels.NeuroscienceLearningNeurologycognitive deficitsMemoryneuropsychiatric disordersCognitiontranslation researchanimal modelPsychiatryNeuroscience.Ales Stuchlikauth1374730Stuchlik AlesSumiyoshi TomikiUkMaJRUBOOK9910137098703321Cognitive deficits in schizophrenia and other neuropsychiatric disorders3408233UNINA04228oam 2200589 450 991081941170332120240131150303.01-317-47038-91-315-70428-51-317-47039-71-282-11956-797866121195690-7656-2446-X10.4324/9781315704289(OCoLC)436980016(MiFhGG)GVRL2YVI(EXLCZ)99100000000075451120061121d2008 uy 0engurun|---uuuuatxtccrForeign aid and foreign policy lessons for the next half-century /edited by Louis A. Picard, Robert Groelsema, and Terry F. BussArmonk, N.Y. :M.E. Sharpe,2008.1 online resource (xiii, 450 pages) illustrationsTransformational trends in governance and democracy"First published 2008 by M.E. Sharpe"--t.p. verso.Print version: Foreign aid and foreign policy: lessons for the next half-century London ; Routledge, 2015. (OCoLC)76794825 0-7656-2044-8 0-7656-2043-X Includes bibliographical references and index.About the Academy; Foreign Aid and Foreign Policy; Contents; Preface; 1. U.S. Foreign Aid Priorities Goals for the Twenty-First Century; The Merger of USAID and the Department of State; Post-September 11 Developments; The Nature of Foreign Aid; A Mixed Record for Foreign Aid; Searching for Direction; Why Foreign Aid Fails; The Potential for Success?; Note; References; Part 1. Foreign Aid and Foreign Policy Debates; 2. Foreign Aid and Security: A Renewed Debate?; 3. Foreign Aid in the Twenty-First Century: What Purposes?4. Foreign Aid in the National Interest: The Importance of Democracy and Governance5. Foreign Aid in Comparative Perspective: Regime Dynamics and Donor Interests; Part 2. Case Studies in Foreign Aid; 6. Building Local Governance in Iraq: Limits and Lessons; 7. Foreign Aid and South Asia: The Case of Pakistan; 8. Donors, Public-Sector Reform, and Decentralization: Democracy and Civil Society in Ghana; 9. Why Foreign Aid to Haiti Failed-and How toDo It Better Next Time; 10. USAID and Eastern Europe: Something Old, Something New11. Post-Millennium U.S. Aid for Africa: Reconciling Freedom and Security, Theirs and OursPart 3. Organizational Dynamics andForeign Aid Policy; 12. Transformations in U.S. Foreign Economic Assistance; 13. Higher Education, Capacity Building, and Aid: Lessons Learned; 14. NGOs in the Foreign Aid System; 15. The Millennium Challenge Account: An Early Appraisal; 16. Deepening Local Democratic Governance: Connecting the Dots in Sub-Saharan Africa; Part 4. International Assistance and Development; 17. Diasporas and Development: What Role for Foreign Aid?18. Remittances, Foreign Aid, and Developing Countries19. Aid and Development: A Conceptual Perspective from Development Economics; 20. Mainstreaming of Democracy and Governance in Foreign Assistance; About the Editors and Contributors; IndexThis timely work presents cutting-edge analysis of the problems of U.S. foreign assistance programs--why these problems have not been solved in the past, and how they might be solved in the future. The expert contributors focus primarily on U.S. foreign assistance and foreign policy as they apply to nation building, governance, and democratization.Transformational trends in governance & democracy.Economic assistance, American21st centuryEconomic assistance, AmericanHistoryCase studiesUnited StatesForeign relations21st centuryUnited StatesForeign relationsCase studiesEconomic assistance, AmericanEconomic assistance, AmericanHistory338.91/73Picard Louis A.Groelsema Robert1950-Buss Terry F.MiFhGGMiFhGGBOOK9910819411703321Foreign aid and foreign policy4110464UNINA