04541nam 2200721 a 450 991081886230332120240516064821.09786613693938978047072023304707202399781280783548128078354097804707179120470717912(CKB)1000000000688090(SSID)ssj0000715204(PQKBManifestationID)11454821(PQKBTitleCode)TC0000715204(PQKBWorkID)10700429(PQKB)10195107(MiAaPQ)EBC703865(Au-PeEL)EBL703865(CaPaEBR)ebr10575679(CaONFJC)MIL369393(OCoLC)797918363(OCoLC)2048134(FINmELB)ELB179125(Perlego)2766646(EXLCZ)99100000000068809020760129d1976 uy 0engurcn|||||||||txtrdacontentcrdamediacrrdacarrierPolypeptide hormones molecular and cellular aspects /editors, F. G. Young [et al.]1st ed.Amsterdam ;New York Elsevier1976Amsterdam ;New York :Elsevier,1976.1 online resource (xii, 388 pages) illustrationsCiba Foundation symposium (new series) ;41"Symposium on the Polypeptide Hormones: Molecular and Cellular Aspects held at the Ciba Foundation, London, 1st-3rd July, 1975"--Participants page."In honour of Sir Frank Young."9780470663332 0470663332 9789021940465 9021940469 Includes bibliographical references and indexes.Polypeptide Hormones: molecular and cellular aspects -- Contents -- Chairman's opening remarks -- Biosynthesis of insulin and glucagon: a view of the current state of the art -- Discussion -- Molecular evolution of the polypeptide hormones -- Discussion -- Prohormones of β-melanotropin (β-melanocyte-stimulating hormone, β-MSH) and corticotropin (adrenocorticotropic hormone, ACTH) : structure and activation -- Discussion -- The nature of pituitary large growth hormone as studied by immunoabsorption -- Discussion -- Isolation of a biologically active messenger RNA : preparation from fish pancreatic islets by oligo(2'-deoxyrhymidylic acid) affinity chromatography -- Discussion -- The control of insulin release by sugars -- Discussion -- The mode of action of adenosine 3': 5'-cyclic phosphate in the regulation of insulin secretion -- Discussion -- Multiple forms of corticotropin (adrenocorticotropic hormone, ACTH) and their significance -- Discussion -- Carboxypeptidase B-like and trypsin-like activities in isolated rat pancreatic islets -- Discussion -- New concepts in the formation, regulation of release, and metabolism of parathyroid hormone -- Discussion -- Structure and structure-function relationships in glycoprotein hormones -- Discussion -- Heterogeneity of the gastrins in blood and tissue -- Discussion -- Membrane topology as revealed by the binding of macromolecules -- Discussion -- Protein phosphorylation and hormone action -- Discussion -- Growth-promoting actions of peptide hormones -- Discussion -- General discussion I : Somatostatin-clinical implications Cells containing somatostatin in the pancreas and the gastrointestinal tract -- Gastrointestinal effects of somatostatin -- Somatostatin and diabetes mellitus -- General discussion II: Peptide metabolism -- Post-synthetic modification of peptides -- Secretion and processing.Closing remarks -- Index of contributors -- Subject index.The Novartis Foundation Series is a popular collection of the proceedings from Novartis Foundation Symposia, in which groups of leading scientists from a range of topics across biology, chemistry and medicine assembled to present papers and discuss results. The Novartis Foundation, originally known as the Ciba Foundation, is well known to scientists and clinicians around the world. Ciba Foundation symposium ;new ser. 41.Peptide hormonesCongressesPeptide hormones599/.01/927Young Frank939223MiAaPQMiAaPQMiAaPQBOOK9910818862303321Polypeptide hormones2117157UNINA