01184nam0 2200277 i 450 VAN007199220221128081114.967978-04-7194-369-320091019d1994 |0itac50 baengUS|||| |||||Bioinorganic chemistryinorganic elements in the chemistry of lifean introduction and guideWolfgang Kaim, Brigitte SchwederskiChichesterWiley1994IX, 401 p.ill.26 cmGBChichesterVANL000049546Chimica inorganica22KaimWolfgangVANV056866724665SchwederskiBrigitteVANV056867724664Wiley <editore>VANV108092650ITSOL20230915RICABIBLIOTECA DEL DIPARTIMENTO DI SCIENZE E TECNOLOGIE AMBIENTALI BIOLOGICHE E FARMACEUTICHEIT-CE0101VAN17VAN0071992BIBLIOTECA DEL DIPARTIMENTO DI SCIENZE E TECNOLOGIE AMBIENTALI BIOLOGICHE E FARMACEUTICHE17CONS Ca110 17BIB1405 20091030 BuonoBioinorganic chemistry1415053UNICAMPANIA02292nam 2200577 450 991081841790332120200520144314.02-7420-1331-8(CKB)3710000000088070(EBL)3317972(SSID)ssj0001340605(PQKBManifestationID)11716527(PQKBTitleCode)TC0001340605(PQKBWorkID)11381269(PQKB)10706942(MiAaPQ)EBC3317972(Au-PeEL)EBL3317972(CaPaEBR)ebr10836918(OCoLC)874163715(PPN)198673167(EXLCZ)99371000000008807020140217h20122012 uy| 0engur|n|---|||||txtccrEnvironmental changes & human health 2012 zoonotic and vector-borne diseases : 23rd March 2012 symposium's proceedings - MonacoMontrouge, France :Institut Pasteur,[2012]20121 online resource (81 p.)Hors collectionDescription based upon print version of record.2-7420-1083-1 Includes bibliographical references.""Environmental Changes & Human Health 2012 - Zoonotic and Vector-borne Diseases""; ""Contents""; ""An historical perspective on environmental change and vector-borne disease""; ""Modelling emergence of vector-borne diseases in Europe""; ""Climate-driven infectious diseases in a changing human landscape: two case studies on cholera and malaria""; ""Environmental changes and the emergence of zoonotic infections in humans""; ""Human migrations and adaptation to the environment: a genetic view""; ""Vector-borne diseases and international transport""Hors collectionEnvironmental changes and human health 2012ZoonosesVector controlCommunicable diseasesTransmissionZoonoses.Vector control.Communicable diseasesTransmission.MiAaPQMiAaPQMiAaPQBOOK9910818417903321Environmental changes & human health 20124123255UNINA04133nam 22006133 450 991101978550332120241207060246.0978352783838735278383849783527838394352783839297835278383703527838376(MiAaPQ)EBC31812765(Au-PeEL)EBL31812765(CKB)36822877300041(OCoLC)1477220064(Perlego)4668906(Exl-AI)31812765(EXLCZ)993682287730004120241207d2025 uy 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierTrends in MRNA Vaccine Research1st ed.Newark :John Wiley & Sons, Incorporated,2025.©2025.1 online resource (428 pages)Trends in Drug Discovery Series9783527350582 3527350586 Cover -- Title Page -- Copyright -- Contents -- Preface -- Preface from the Volume Editors -- Part I How mRNA Vaccines Work -- Chapter 1 A Historical Overview on mRNA Vaccine Development -- 1.1 Introduction -- 1.2 The Path of mRNA as an Unstable and Toxic Product to a New Class of Medicine -- 1.2.1 The Discovery and In Vitro Production of mRNA -- 1.2.2 The Inflammatory Nature of mRNA -- 1.3 How Studying Lipid Bilayer Structures in Cell Membranes Gave Rise to the Eventual Development of Lipid Nanoparticles for RNA Delivery -- 1.3.1 From Biological Cell Membranes to Liposomal Drugs -- 1.3.2 Ionizable Lipid Nanoparticles for Systemic Delivery of Nucleic Acids -- 1.4 The Journey of Developing Clinical mRNA Vaccines -- 1.5 Concluding Remarks -- References -- Chapter 2 Immune Responses to mRNA Vaccine -- 2.1 Introduction -- 2.2 Innate Sensing of RNA Molecules -- 2.3 Innate Immune Response to mRNA Vaccines -- 2.3.1 Innate Immune Response in Humans -- 2.3.2 Tissue Innate Immune Response in Mice -- 2.4 mRNA Design and Innate Immunity -- 2.4.1 Cap -- 2.4.2 Untranslated Regions -- 2.4.3 Poly(A) -- 2.4.4 Coding Sequence -- 2.5 Optimization and Production of mRNA for an Adequate Innate Immune ResponseGenerated by AI.The authoritative guide to the revolutionary concept behind the successful Covid-19 vaccines In Trends in mRNA Vaccine Research, a team of distinguished researchers delivers a practical and up-to-date discussion of the biochemical and biomedical foundations of mRNA vaccines. They also explore the manufacturing conditions required for successful vaccine development and review recent progress in a variety of medical fields, including vaccines against pathogens like SARS-CoV-2, HIV, plasmodium, Mycobacterium tuberculosis, as well as anticancer vaccines. Volume highlights include: * A historical overview of mRNA vaccine development * Immune responses to modified or unmodified mRNA vaccines * A description of the different mRNA vaccine platforms * Latest data on current mRNA vaccine developments against infectious diseases and cancer Perfect for medicinal chemists, immunologists, and epidemiologists, Trends in mRNA Vaccine Research will also benefit researchers and scientists working in the pharmaceutical industry, as well as cancer researchers with an interest in vaccine development. Trends in Drug Discovery SeriesCOVID-19 vaccinesGenerated by AIMessenger RNAGenerated by AICOVID-19 vaccinesMessenger RNA615.372Szabo Gabor Tamas1842735Pardi Norbert1842736Fischer János881301Klein Christian426675Childers Wayne E1838514MiAaPQMiAaPQMiAaPQBOOK9911019785503321Trends in MRNA Vaccine Research4422945UNINA