03256nam 2200661 a 450 991081818170332120200520144314.01-107-35757-81-107-23614-21-107-34170-11-107-34903-61-107-34795-51-139-16934-31-107-34545-61-299-40338-71-107-34420-4(CKB)2550000001018044(EBL)1139693(OCoLC)833768528(SSID)ssj0000856567(PQKBManifestationID)11469840(PQKBTitleCode)TC0000856567(PQKBWorkID)10817788(PQKB)10825379(UkCbUP)CR9781139169349(MiAaPQ)EBC1139693(Au-PeEL)EBL1139693(CaPaEBR)ebr10679204(CaONFJC)MIL471588(OCoLC)847620563(PPN)261359851(EXLCZ)99255000000101804420121108d2013 uy 0engur|||||||||||txtrdacontentcrdamediacrrdacarrierPaternal influences on human reproductive success /[edited by] Douglas T. Carrell1st ed.Cambridge Cambridge University Press20131 online resource (xi, 195 pages) digital, PDF file(s)Title from publisher's bibliographic system (viewed on 05 Oct 2015).1-107-02448-X Includes bibliographical references and index.section 1. Advances in understanding the male gamete -- section 2. The influence of aging and environmental factors on male reproductive success -- section 3. Clinical laboratory concepts and considerations.Historically, sperm have been seen as simply a mechanism of transferring a haploid set of chromosomes to the oocyte. However, data from assisted reproduction therapies (ART) have demonstrated that in many couples the sperm appears to be responsible for abnormal embryogenesis. Recent advances in genetic and epigenetic techniques have identified key mechanisms by which the sperm, and the DNA carried by the sperm, can affect early embryonic development. Paternal Influences on Human Reproductive Success examines the genetic and epigenetic influences on embryogenesis, as well as practical clinical factors related to the male contribution to reproductive success. It also provides 'cutting edge' data and analysis of recent evaluations of the role of advanced paternal age, environmental influences and lifestyle factors on male reproductive fitness, making this an invaluable text for physicians treating patients for infertility, recurrent pregnancy loss, and developmental anomalies, as well as basic scientists studying embryogenesis and spermatogenesis.Infertility, MaleSocial aspectsInfertility, MaleSocial aspects.616.6/921Carrell Douglas T1759255MiAaPQMiAaPQMiAaPQBOOK9910818181703321Paternal influences on human reproductive success4197659UNINA