03329nam 2201069z- 450 991034683940332120231214133435.0(CKB)4920000000095246(oapen)https://directory.doabooks.org/handle/20.500.12854/53851(EXLCZ)99492000000009524620202102d2019 |y 0engurmn|---annantxtrdacontentcrdamediacrrdacarrierMolecular Modeling in Drug DesignMDPI - Multidisciplinary Digital Publishing Institute20191 electronic resource (220 p.)3-03897-614-8 This book is a printed edition of the Special Issue Molecular Modeling in Drug Design that was published in Moleculesmetadynamicsnatural compoundsvirtual screeningprobe energiesmolecular dynamics simulationhuman ecto-5?-nucleotidaseneural networksquantitative structure-activity relationship (QSAR)artificial intelligenceallosterismin silico screeningdrug discoveryamyloid fibrilsmechanical stabilityadenosine receptorsadenosine receptorligand bindingpromiscuous mechanismAutoGriddynamic light scatteringresultant dipole momentdensity-based clusteringAlzheimer’s diseasedrug designbiophenolsenzymatic assaysall-atom molecular dynamics simulationfragment screeningadenosinedockingmolecular dockingcosolvent molecular dynamicsturbidimetrysqualene synthase (SQS)molecular recognitionprotein-peptide interactionsextracellular loopsFimHbinding affinityrational drug designde novo designhyperlipidemiaAR ligandsaggregationproperty predictionPPI inhibitiondeep learningproteinsquantitative structure-property prediction (QSPR)protein protein interactionsboron clustertarget-focused pharmacophore modelingligand–protofiber interactionsstructure-based drug designscoring functiongrid mapssolvent effectadhesionmolecular dynamicsTraditional Chinese Medicinesteered molecular dynamicsinteraction energyEphA2-ephrin A1molecular modelingmethod developmentWade Rebeccaauth1292421Salo-Ahen OutiauthBOOK9910346839403321Molecular Modeling in Drug Design3022288UNINA02814nam 2200565 a 450 991081817180332120200520144314.0978145228056114522805689781452212074145221207497814416538711441653872(CKB)2560000000013220(EBL)1157268(MiAaPQ)EBC1157268(EXLCZ)99256000000001322020080201d2008 uy 0engur|n|---|||||txtrdacontentcrdamediacrrdacarrierThe one-minute temper tantrum solution strategies for responding to children's challenging behaviors /Ronald Mah1st ed.Thousand Oaks, CA Corwin Pressc20081 online resource (161 p.)Description based upon print version of record.9781412957212 1412957214 Includes bibliographical references (p. 135-139) and index.Cover -- Contents -- Acknowledgments -- About the Author -- Introduction -- Chapter 1 - Orderly Assessment to Successful Intervention: Where Do You Start? Where Do You End Up? -- Chapter 2 - Developmental Factors: Developmental Energy Will Reassert -- Chapter 3 - Situational, Physical, and Disruption Factors: 2 + 1 = Trouble! -- Chapter 4 - Temperamental Factors: They Were Born That Way! -- Chapter 5 - Systemic Factors: The Savior -- Chapter 6 - Specific or Specialized Factors and Moral Factors: Try Harder -- Chapter 7 - Four Types of Temper Tantrums!: Not Always About Power and Control -- Chapter 8 - Manipulative Tantrums: Power and Control -- Chapter 9 - Upset Temper Tantrums: Distress -- Chapter 10 - Helpless Temper Tantrums: Not Distress but Despair -- Chapter 11 - Stress and the Cathartic Tantrum: Releasing the Cathartic Tantrums -- Chapter 12 - Getting It Wrong and Getting It Right -- Conclusion -- References -- Index.This resource examines developmental, situational, physical, and temperamental factors that can trigger tantrums and provides effective interventions to help teachers avoid long-term negative consequences for children.Temper tantrums in childrenAnger in childrenAttitude change in childrenChild rearingTemper tantrums in children.Anger in children.Attitude change in children.Child rearing.370.15/28Mah Ronald1682208MiAaPQMiAaPQMiAaPQBOOK9910818171803321The one-minute temper tantrum solution4079803UNINA