06674nam 2200661Ia 450 991081701560332120200520144314.00-309-17442-21-280-18682-897866101868220-309-59153-80-585-02408-1(CKB)110986584752214(OCoLC)42329048(CaPaEBR)ebrary10055586(SSID)ssj0000130027(PQKBManifestationID)11148385(PQKBTitleCode)TC0000130027(PQKBWorkID)10081844(PQKB)11302540(Au-PeEL)EBL3376390(CaPaEBR)ebr10055586(OCoLC)923263435(MiAaPQ)EBC3376390(EXLCZ)9911098658475221419980325d1998 uy 0engurcn|||||||||txtrdacontentcrdamediacrrdacarrierContraceptive research, introduction, and use lessons from Norplant /Polly F. Harrison and Allan Rosenfield, editors ; Subcommittee for Workshop on Implant Contraceptives: An illuminating case study in current dilemmas and possibilities, Committee on Contraceptive Research and Development, Division of Health Sciences Policy, Institute of Medicine1st ed.Washington, D.C. National Academy Press19981 online resource (vii, 120 pages) illustrationsBased on a workshop held in April 1997.0-309-05985-2 Includes bibliographical references.Contraceptive Research, Introduction, and Use -- Copyright -- Acknowledgments -- Contents -- 1 Introduction -- 2 Workshop Report -- EFFICACY AND SAFETY -- Efficacy -- Safety -- Major Health-Related Events -- Significant Health-Related Problems -- Silicone Biocompatibility -- Progestin Effects on Vaginal HIV Transmission -- WHO USES NORPLANT AND HOW -- User Populations -- Method Continuation and Discontinuation -- Side Effects as Factors -- User Satisfaction -- Barriers to Discontinuation -- Cost and Cost-Effectiveness -- Effects of Media Coverage and Litigation on Norplant Use -- INSERTION AND REMOVAL: EXPERIENCE AND IMPLICATIONS -- Technical Aspects -- Case Experiences -- Rates of Complicated Removals -- Implications -- CONSUMER PERSPECTIVES -- Communication and Quality of Care -- Quality of Care -- Informed Decision-Making -- Importance -- Content -- Special Challenges -- Potential for Abuse -- Consumer Involvement -- NEW APPROACHES -- Reproductive Health Technologies Project's "Boom and Bust Initiative -- The WHO Strategic Approach to Contraceptive Introduction -- A ''Government Standards Defense -- 3 Workshop Summary and Analysis -- DATA REVIEW -- Efficacy -- Safety -- User Profiles -- Side Effects -- Continuation and Discontinuation -- User Satisfaction -- Postmarketing Surveillance -- Cost-Effectiveness -- LESSONS LEARNED -- NEXT STEPS: AREAS FOR CONSIDERATION AND ACTION -- Areas for Strengthening or Expansion -- 1. Clinical Research -- 2. Market Research -- 3. "Pre-introduction -- 4. Informed Decision-Making -- 5. Postmarketing Surveillance -- Areas for New Initiative -- 6. Credentialing -- 7. Core Guidelines for Long-Acting Contraceptives -- 8. Costs -- 9. Product Liability -- FINAL COMMENT -- ENDNOTES -- Appendixes -- A Presentation Summaries -- Presentation 1 -- Background -- Methodology -- Findings -- Age and Educational Levels.Major Health-Related Events -- Significant Health-Related Problems -- Continuation and Removals -- Efficacy -- Conclusions -- Presentation 2 -- Background -- Methodology -- Findings -- Pregnancy and Continuation Rates -- Reasons for Discontinuation -- Removal Difficulties -- Mortality and Hospitalization -- Conclusions -- Presentation 3 -- Background -- Methodology -- Findings -- Conclusions -- Presentation 4 -- Background -- Findings -- Composition -- Inflammatory Wound Healing Reaction and Blood Protein Absorption -- Conclusions -- Presentation 5 -- Background -- Methodology -- Findings -- Conclusions -- Presentation 6 -- Background and Methodology -- Findings -- Conclusions -- Presentation 7 -- Background -- Findings -- Conclusions -- Presentation 8 -- Background -- Methodology -- Findings and Conclusions -- Sample Characteristics -- Continuation and Discontinuation -- Media Effects -- Norplant and Coercion -- Presentation 9 -- Background -- Methodology -- Findings -- Sample Characteristics -- Continuation and Discontinuation -- The Question of Coercion -- Postdiscontinuation Experience -- Conclusions -- Presentation 10 -- Background -- Methodology -- Findings -- Conclusions -- Presentation 11 -- Background -- Removal Techniques -- Standard Technique -- Pop-Out Technique -- U Technique -- Removal Difficulties and Training -- Conclusions -- Presentation 12 -- Background -- Methodology -- Findings -- Conclusions -- Presentation 13 -- Background -- Methodology -- Findings -- Conclusions -- Presentation 14 -- Background -- Findings -- Choice -- Removal on Demand -- Tracking Capacity -- Conclusions -- Presentation 15 -- Background -- Discussion -- The Role of the FDA -- The Potential Role of a Federal Standards Defense -- ENDNOTES -- B Norplant: Historical Background -- THE TECHNOLOGY -- HISTORY -- ENDNOTES -- C Workshop Agenda.Implant Contraceptives: An Illuminating Case Study in Current Dilemmas and Possibilities 7-8 April 1997 -- NATIONAL ACADEMY OF SCIENCES INSTITUTE OF MEDICINE -- WORKSHOP -- PARTICIPANTS.Contains an examination of Norplant's efficacy and safety, its user populations, training for insertion and removal, consumer perspectives - quality of care, informed decisionmaking, and consumer involvement - and approaches to contraceptive development and introduction. This book's appendix contains summaries of 17 workshop presentations.ContraceptionResearchCongressesBirth controlResearchCongressesContraceptionResearchBirth controlResearch613.9/4Harrison Polly F1646797Rosenfield Allan1646798Institute of Medicine (U.S).Committee on Contraceptive Research and Development.Institute of Medicine (U.S.).Subcommittee for Workshop on Implant Contraceptives : an Illuminating Case Study in Current Dilemmas and Possibilities.MiAaPQMiAaPQMiAaPQBOOK9910817015603321Contraceptive research, introduction, and use3993987UNINA