03886nam 2200637Ia 450 991081649130332120240516120806.01-280-58641-997866136162411-4443-5562-71-4443-5543-0(CKB)2670000000154959(EBL)861626(OCoLC)777375710(SSID)ssj0000612087(PQKBManifestationID)11362726(PQKBTitleCode)TC0000612087(PQKBWorkID)10685963(PQKB)11465483(MiAaPQ)EBC861626(Au-PeEL)EBL861626(CaPaEBR)ebr10538630(CaONFJC)MIL361624(EXLCZ)99267000000015495920111102d2012 uy 0engur|n|---|||||txtccrImmunotherapy in transplantation principles and practice /edited by Bruce Kaplan, Gilbert J. Burckart, Fadi G. Lakkis1st ed.West Sussex John Wiley20121 online resource (485 p.)Description based upon print version of record.1-4051-8271-7 Includes bibliographical references and index.Immunotherapy in Transplantation: Principles and Practice; Contents; List of Contributors; Preface; Part 1 Transplantation Immunobiology; 1 The Immune Response to a Transplanted Organ: An Overview; 2 Antigen Presentation in Transplantation; 3 The T Cell Response to Transplantation Antigens; 4 The B Cell Response to Transplantation Antigens; 5 The Innate Response to a Transplanted Organ; 6 Regulation of the Alloimmune Response; Part 2 Transplantation Clinical Pharmacology; 7 Pharmacokinetics; 8 Therapeutic Drug Monitoring for Immunosuppressive Agents9 Pharmacometrics: Concepts and Applications to Drug Development10 Pharmacogenomics and Organ Transplantation; 11 Study Design/Process of Development: Clinical Studies; Part 3 Agents; 12 Corticosteroids; 13 Azathioprine; 14 Pharmacokinetic and Pharmacodynamic Properties of Mycophenolate; 15 Cyclosporine: Molecular Action to Clinical Therapeutics; 16 Tacrolimus; 17 Inhibitors of Mammalian Target of Rapamycin; 18 Inhibitors Targeting JAK3; 19 Cyclophosphamide; 20 Application of Antisense Technology in Medicine; 21 The Role of Ganciclovir in Transplantation22 Transplantation Immunotherapy with Antithymocyte Globulin (ATG)23 The Role of Alemtuzumab in Solid Organ Transplantation; 24 Rituximab, an Anti-CD20 Monoclonal Antibody; 25 The Anti-Interleukin 2 Receptor Antibodies; 26 Infliximab/Anti-TNF; 27 CTLA4-Ig; 28 Combination and Adjuvant Therapies to Facilitate the Efficacy of Costimulatory Blockade; 29 Intravenous Immunoglobulin (IVIG) a Modulator of Immunity and Inflammation with Applications in Solid Organ Transplantation; Index; Color PlatesThis comprehensive reference source will benefit all transplant specialists working with pharmacologic and biologic agents that modulate the immune system. Compiled by a team of world-renowned editors and contributors covering the fields of transplantation, nephrology, pharmacology, and immunology, the book covers all anti-rejection drugs according to a set template and includes the efficacy of each for specific diseases.ImmunotherapyTransplantation immunologyImmunotherapy.Transplantation immunology.615.37Kaplan Bruce1958-1416765Burckart Gilbert J1697013Lakkis Fadi G1697014MiAaPQMiAaPQMiAaPQBOOK9910816491303321Immunotherapy in transplantation4077404UNINA