02879nam 2200541 450 991081588360332120231025162411.01-118-87493-51-118-87492-71-118-87490-0(CKB)4330000000007355(MiAaPQ)EBC5405939(NjHacI)994330000000007355(BIP)061473171(EXLCZ)99433000000000735520180620d2018 uy 0engurcnu||||||||txtrdacontentcrdamediacrrdacarrierSample sizes for clinical, laboratory and epidemiology studies /David Machin, [and three others]Fourth edition.Hoboken, New Jersey :Wiley,[2018]1 online resource (409 pages)THEi Wiley ebooks.1-118-87494-3 Includes bibliographical references and index.Ranking the Multiple Endpoints2.5 Repeated Significance Tests; Bonferroni Correction; 2.6 Epidemiological Studies; 2.7 The Protocol and Publication; 2.8 Ethical Issues and Sample Size; References; Chapter 3 Binary Outcomes; 3.1 Introduction; 3.2 Comparing Proportions; Effect Size; Analysis; χ2 Test; Fisher's Exact Test; 3.3 One Proportion Known; χ2 Test; 3.4 Bibliography; 3.5 Examples and Use of the Tables; Table 3.1 and Equations 3.2 and 3.3; Table 3.1 and Equations 3.2, 3.3, 3.4 and 3.5; Equations 3.2 and 3.5; Table 3.2 and Equations 3.1, 3.2, 3.3 and 3.4; Equations 3.1, 3.3 and 3.4."Sample Size Tables for Clinical Studies provides the statistical tools - equations, formulae and numerical tables - statisticians and researchers need to design and plan valid clinical studies and to accurately analyse publishable results. It explains the sample size considerations that are important when designing and planning any type of clinical study. It clearly outlines the methodologies employed, within the context of clinical studies and trials, and provides relevant practical examples. Each chapter provides and explains sets of sample size tables. They also include Bibliography and References sections directed towards further guidance on the principles discussed and more detailed explanations"--Provided by publisher.Clinical trialsResearchStatisticsReferenceMathematicsClinical trials.615.5072/4Machin David1939-520765Campbell Michael J.1950-Tan Say BengTan Sze HueyMiAaPQMiAaPQMiAaPQBOOK9910815883603321Sample sizes for clinical, laboratory and epidemiology studies3993460UNINA