03101nam 2200685 a 450 991081449900332120240516140903.09786613620774978128059094812805909479781118305409111830540X9781119942986111994298597811199429791119942977(CKB)2670000000170075(EBL)881533(OCoLC)770696945(SSID)ssj0000635051(PQKBManifestationID)11451926(PQKBTitleCode)TC0000635051(PQKBWorkID)10643250(PQKB)11648434(MiAaPQ)EBC881533(DLC) 2012000005(Au-PeEL)EBL881533(CaPaEBR)ebr10630592(CaONFJC)MIL362077(Perlego)1009578(EXLCZ)99267000000017007520111223d2012 uy 0engur|n|---|||||txtccrEvidence synthesis for decision making in healthcare /Nicky J. Welton ... [et al.]1st ed.Chichester, West Sussex John Wiley & Sons20121 online resource (296 p.)Statistics in practiceDescription based upon print version of record.9780470061091 047006109X Includes bibliographical references and index.Introduction -- Bayesian methods and winBUGS -- Introduction to decision models -- Meta-analysis using Bayesian methods -- Exploring between study heterogeneity -- Model critique and evidence consistency in random effects meta-analysis -- Evidence synthesis in a decision modelling framework -- Multi-parameter evidence synthesis in epidemiological models -- Mixed treatment comparisons -- Markov models -- Generalised evidence synthesis -- Expected value of information for research prioritisation and study design.In the evaluation of healthcare, rigorous methods of quantitative assessment are necessary to establish interventions that are both effective and cost-effective. Usually a single study will not fully address these issues and it is desirable to synthesize evidence from multiple sources. This book aims to provide a practical guide to evidence synthesis for the purpose of decision making, starting with a simple single parameter model, where all studies estimate the same quantity (pairwise meta-analysis) and progressing to more complex multi-parameter structures (including meta-regression, mixeStatistics in practice.Evidence-based medicineStatistical methodsEvidence-based medicineStatistical methods.362.1068/4Welton Nicky J1618106MiAaPQMiAaPQMiAaPQBOOK9910814499003321Evidence synthesis for decision making in healthcare3949637UNINA