03645nam 2200625 450 991081312740332120230807211326.01-118-32348-31-118-32343-21-118-32347-5(CKB)3710000000576488(EBL)4335873(SSID)ssj0001600635(PQKBManifestationID)16308341(PQKBTitleCode)TC0001600635(PQKBWorkID)12768031(PQKB)10750742(PQKBManifestationID)14279825(PQKBWorkID)13976937(PQKB)21680891(MiAaPQ)EBC4335873(DLC) 2015010035(Au-PeEL)EBL4335873(CaPaEBR)ebr11140622(CaONFJC)MIL888568(OCoLC)935920174(EXLCZ)99371000000057648820160122h20152015 uy 0engur|n|---|||||txtccrClinical trials in older people /edited by Antonio Cherubini [and five others] ; contributors Heather Allore [and thirty five others]Chichester, England :Wiley Blackwell,2015.©20151 online resource (308 p.)Description based upon print version of record.1-118-32349-1 Includes bibliographical references at the end of each chapters and index.The exclusion of older subjects from clinical trials : the predict study / Antonio Cherubini, Peter Crome -- Clinical trials in older adults : a point of view from the industry / Susanna Del Signore, Philippe Guillet -- Ethical issues in clinical trials involving older subjects : the right to participate in clinical trials and have access to care; the protection of vulnerable subjects and the issue of informed consent / Emmanuel Hirsch, Paul-Loup Weil-Dubuc -- Mastering the design of clinical trials for older persons : the tension between external validity and feasibility / Luigi Ferrucci, Stephanie Studenski -- Pharmacokinetic and pharmacodynamic studies in older adults / Arduino A Mangoni, Paul AF Jansen, Stephen H.D. Jackson -- The role of comprehensive geriatric assessment of older adults in clinical studies / Graziano Onder, Agnese Collamati, Andrea Poscia, Roberto Bernabei -- Statistical issues in designing and interpreting clinical trials in older adults / Heather Allore, Mark A. Espeland, Michael E. Miller -- Challenges in implementing large-scale clinical trials in moderately functioning older adults / Stephen D. Anton, Sandrine Sourdet, Marco Pahor, & Todd Manini -- Clinical trials in Alzheimer's disease / Julien Delrieu , Bruno Vellas -- Clinical trials in late-life mood disorders / Lucio Ghio, Werner Natta, Marco Vaggi, Luigi Ferrannini -- Clinical trials for conditions of low muscle mass and strength / Stephanie Studenski, Rosaly Correa-de-Araujo and Luigi Ferrucci -- Clinical trials of cancer treatment in the elderly / Lodovico Balducci, Iordanis Gravanis, Francesco Pignatti -- Clinical trials in nursing homes : challenges and practical solutions / Sandra Simmons, Barbara Resnik, John Schnelle, Joe Ouslander.Clinical trialsGerontologyResearchClinical trials.GerontologyResearch.610.72/40846Cherubini Antonio1966-Allore HeatherMiAaPQMiAaPQMiAaPQBOOK9910813127403321Clinical trials in older people4013623UNINA