04962nam 2200685 450 991081298410332120230807220142.01-118-86327-51-118-86326-71-118-86328-3(CKB)3710000000440565(EBL)2081171(SSID)ssj0001515161(PQKBManifestationID)12621949(PQKBTitleCode)TC0001515161(PQKBWorkID)11481468(PQKB)11575136(PQKBManifestationID)16037134(PQKB)24072398(MiAaPQ)EBC4039372(MiAaPQ)EBC2081171(DLC) 2015007606(Au-PeEL)EBL4039372(CaPaEBR)ebr11112957(CaONFJC)MIL809607(OCoLC)904012321(EXLCZ)99371000000044056520151105h20152015 uy 0engur|||||||||||txtccrClinical guide to transplantation in lymphoma /edited by Bipin N. Savani, MD, Mohamad Mohty, MD, PhDChichester, [England] :Wiley Blackwell,2015.©20151 online resource (288 p.)Description based upon print version of record.1-118-86332-1 Includes bibliographical references at the end of each chapters and index.Title page; Copyright page; Contents; List of contributors; Foreword; Introduction; Declaration of commercial interest; References; Section 1 Transplantation in lymphomas; Chapter 1 Lymphoma and transplantation: historical perspective; Brief history of hematopoietic cell transplantation; History of autologous HCT in non-Hodgkin lymphoma; History of autologous HCT in Hodgkin lymphoma; History of allogeneic HCT in lymphoma; General historical considerations; References; Chapter 2 Lymphoma: working committee and data reporting after transplantation in lymphoma; Introduction; Registry structureWorking committees Data reporting; Overcoming challenges to data reporting; Flow of data; Data quality; The Lymphoma Working Committee; Statistical methods; Type of data; Intervals and patient selection; Unadjusted comparison; Adjusted comparison; Selected examples from the CIBMTR Lymphoma Committee; Value for young investigators; Value for public and other stakeholders; Conclusion; References; Chapter 3 Use of transplantation in lymphoma: adults; Introduction; Hodgkin lymphoma; Non-Hodgkin lymphoma; Diffuse large B-cell lymphoma; Follicular lymphoma; Histologic transformation to DLBCLMantle cell lymphoma Burkitt lymphoma; Primary CNS lymphoma; Peripheral T-cell lymphoma; Prognostic tools; Maintenance therapies; Novel therapies; Conclusions; References; Chapter 4 Hematopoietic stem cell transplantation for lymphoma in children, adolescents, and young adults; Introduction; Principles of autologous and allogeneic HSCT in pediatric lymphomas; Hodgkin lymphoma; Lymphoblastic lymphoma; Anaplastic large-cell lymphoma; Mature B-cell lymphomas: Burkitt lymphoma, diffuse large B-cell lymphoma, and primary mediastinal B-cell lymphoma; Future directions; Conclusions; ReferencesChapter 5 Preparative regimens for lymphoma: autologous hematopoietic stem cell transplantation Rationale for chemotherapy dose intensification for disease eradication; Traditional preparative regimens; Incorporation of monoclonal antibodies in autologous HCT preparative regimens; Rituximab; Monoclonal antibodies conjugated to radionuclide; Novel agents used in preparative regimens; Future directions; References; Chapter 6 Preparative regimens for lymphoma: allogeneic hematopoietic stem cell transplantation; Introduction; Myeloablative conditioning regimens for lymphomasReduced-intensity conditioning regimens RIC allo-HCT in diffuse large B-cell lymphoma; RIC allo-HCT for follicular lymphoma; RIC allo-HCT in mantle cell lymphoma; RIC allo-HCT in Hodgkin lymphoma; Incorporating monoclonal antibodies in preparative regimens for allo-HCT; Alternative donor sources; Umbilical cord blood cells; Haploidentical transplantation; Vaccine strategies in allo-HCT; Discussion and future direction; References; Chapter 7 Pretransplantation evaluation, comorbidities, and nondisease-related eligibility criteria for transplantation in lymphoma; Introduction; Initial stepsPreparation for transplant center evaluationLymphomasSurgeryStem cellsTransplantationLymphomasSurgery.Stem cellsTransplantation.616.99446Savani Bipin N.Mohty MohamadMiAaPQMiAaPQMiAaPQBOOK9910812984103321Clinical guide to transplantation in lymphoma4018578UNINA04071nam 22005655 450 991029842010332120200705145430.03-319-77982-610.1007/978-3-319-77982-9(CKB)4100000004243831(DE-He213)978-3-319-77982-9(MiAaPQ)EBC5403420(PPN)22740646X(EXLCZ)99410000000424383120180526d2018 u| 0engurnn|008mamaatxtrdacontentcrdamediacrrdacarrierThe ABCs of Gene Cloning /by Dominic W. S. Wong3rd ed. 2018.Cham :Springer International Publishing :Imprint: Springer,2018.1 online resource (XIX, 257 p. 172 illus., 1 illus. in color.) 3-319-77762-9 Fundamentals of Genetic Processes -- Introductory Concepts -- Structures of Nucleic Acids -- Structures of Proteins -- The Genetic Process -- Organization of Genes -- Reading The Nucleotide Sequence of a Gene -- Techniques and Strategies of Gene Cloning -- Enzymes Used in Cloning -- Techniques Used in Cloning -- Cloning Vectors for Introducing Genes into Host Cells -- Transformation -- Isolating Genes for Cloning -- Impact of Gene Cloning -- Improving Tomato Quality by Antisense Rna -- Transgenic Crops Engineered with Insecticidal Activity -- Transgenic Crops Conferred with Herbicide Resistance -- Growth Enhancement in Transgenic Fish -- Impact of Gene Cloning -- Microbial Production of Recombinant Human Insulin -- Finding Disease-Causing Genes -- Human Gene Therapy -- Gene Targeting -- DNA Typing -- Transpharmers - Bioreactors for Pharmaceutical Products -- Animal Cloning -- Human Genome Sequencing -- Manipulating Gene Vector Constructs.Clear and concise, this easy-to-use book offers an introductory course on the language of gene cloning, covering microbial, plant, and mammalian systems. It presents the nuts and bolts of gene cloning in a well-organized and accessible manner. Part I of this book outlines the essentials of biology and genetics relevant to the concept of gene cloning. Part II describes common techniques and approaches of gene cloning, ranging from the basic mechanics of DNA manipulation, vector systems, process transformation, to gene analysis. Part III & IV present application technologies of major impact in agriculture, biomedicine, and related areas. The ABCs of Gene Cloning, Third Edition contains updates including a tutorial chapter on gene-vector construction, methodologies on exome sequencing in finding disease genes, revised topics on gene therapy and whole genome sequencing, new developments for gene targeting and genome editing, as well as the current state of next generation sequencing. With more than 140 illustrations, this new edition provides an invaluable text for students and anyone who have interest in gaining proficiency in reading and speaking the language of gene cloning.Human geneticsFood—BiotechnologyPlant physiologyZoologyHuman Geneticshttps://scigraph.springernature.com/ontologies/product-market-codes/B12008Food Sciencehttps://scigraph.springernature.com/ontologies/product-market-codes/C15001Plant Physiologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L33020Zoologyhttps://scigraph.springernature.com/ontologies/product-market-codes/L25007Human genetics.Food—Biotechnology.Plant physiology.Zoology.Human Genetics.Food Science.Plant Physiology.Zoology.611.01816599.935Wong Dominic W. Sauthttp://id.loc.gov/vocabulary/relators/aut768469BOOK9910298420103321The ABCs of Gene Cloning2529404UNINA