05202nam 2200637Ia 450 991081049190332120230607222108.01-281-86599-097866118659931-84816-144-1(CKB)1000000000537745(EBL)1681669(OCoLC)815741826(SSID)ssj0000216325(PQKBManifestationID)11222305(PQKBTitleCode)TC0000216325(PQKBWorkID)10194878(PQKB)10989729(MiAaPQ)EBC1681669(WSP)0000P231(Au-PeEL)EBL1681669(CaPaEBR)ebr10255901(CaONFJC)MIL186599(EXLCZ)99100000000053774520011016d2001 uy 0engur|n|---|||||txtccrOrganophosphates and health[electronic resource] /editors, Lakshman Karalliedde ... [et al.]London Imperial College Press ;Singapore ;River Edge, NJ Distributed by World Scientific Pub. Co.c20011 online resource (512 p.)Description based upon print version of record.1-86094-270-9 Includes bibliographical references and index.CONTENTS ; Preface ; Acknowledgements ; List of Contributors ; Abbreviations ; Introduction ; 1. Organophosphates: History Chemistry Pharmacology ; 1.1. INTRODUCTION ; 1.2. HISTORY ; 1.3. STRUCTURE AND NOMENCLATURE OF ORGANOPHOSPHATE ANTI ChEs ; 1.4. EFFECTS OF OPs1.5. OPS USED FOR PROPERTIES OTHER THAN ANTIChE ACTIVITY. References ; 2. Socio-Economics Health Issues and Pesticides ; 2.1. Introduction ; 2.2. Role in Control of Vector Borne Diseases ; 2.3. Role in Food Production and Storage ; 2.4. Pesticide-Associated Human Ill-Health2.5. Effects on the Environment and Wild Life 2.6. Insecticide-Related Disease and Global Health Priorities ; 2.7. Role of Industry ; 2.8. Environmental Changes: Effect on Food and Disease ; 2.9. Alternatives ; 2.10. Conclusions ; Acknowledgements ; Other sources of informationThanks 3. Factors Influencing Organophosphate Toxicity in Humans ; 3.1. Introduction ; 3.2. Route of Exposure and Absorption ; 3.3. Dose ; 3.4. Distribution ; 3.5. Metabolism ; 3.6. Tissue binding ; 3.7. Elimination ; 3.8. Alterations in Metabolism ; 3.9. Racemic Mixtures3.10. Concluding Remarks References ; 4. Organophosphorus Chemical Warfare Agents ; 4.1. Introduction ; 4.2. Physical properties ; 4.3. Toxicology ; 4.4. General Toxicity ; 4.5. Effects of Subchronic or Longterm Exposure to Nerve Agents ; 5. Diagnosis ; 6. Treatment7. Prophylaxis of nerve agent poisoning Few chemical compounds created by man have caused greater controversy than organophosphates. Conceived as insecticides, they have also been developed to become the most feared of chemical weapons. The control of vectors of diseases from which millions die or are disabled is heavily dependent on organophosphates, as are efforts to maintain food production in the face of uncontrolled population growth, diminishing arable land and the possibility of global warming. As the toxicity of organophosphates is non-specific, it has caused ill health and death in man, and has contributed to adverse ecoloOrganophosphorus compoundsToxicologyToxicologyOrganophosphorus compoundsToxicology.Toxicology.615.9517Karalliedde Lakshman1716348MiAaPQMiAaPQMiAaPQBOOK9910810491903321Organophosphates and health4111621UNINA