02684nam 2200625 a 450 991080990150332120240417004053.00-309-17817-71-281-30023-397866113002340-309-11013-0(CKB)1000000000714260(SSID)ssj0000279034(PQKBManifestationID)11210640(PQKBTitleCode)TC0000279034(PQKBWorkID)10259467(PQKB)10930698(MiAaPQ)EBC3378332(Au-PeEL)EBL3378332(CaPaEBR)ebr10225174(CaONFJC)MIL130023(OCoLC)923278378(EXLCZ)99100000000071426020080623d2008 uy 0engurcn|||||||||txtccrEmerging safety science workshop summary /Sally Robinson, Robert Pool, and Robert Giffin [rapporteurs] ; Forum on Drug Discovery, Development, and Translation, Board on Health Sciences Policy, Institute of Medicine of the National Academies1st ed.Washington, D.C. National Academies Pressc2008xvi, 134 p. ill. (some col.)Workshop held April 23-24, 2007 in Silver Spring, MD.0-309-11012-2 Includes bibliographical references (p. 115-116).Front Matter -- Reviewers -- Preface -- Contents -- Tables and Figures -- 1 Introduction -- 2 Investigative Toxicology: The State of the Art -- 3 Screening Technologies I: Human Cell-Based Approaches -- 4 Screening Technologies II: Toxicogenomics -- 5 Screening Technologies III: Metabolomics -- 6 Screening Technologies IV: Pharmacogenetics -- 7 Qualifying Biomarkers -- 8 Pharmacovigilance -- 9 Integration -- 10 The Future of Safety Science -- References -- Appendixes -- Appendix A: Workshop Agenda -- Appendix B: Speaker Biographies.DrugsUnited StatesSafety measuresCongressesPharmaceutical biotechnologyUnited StatesCongressesDrugsUnited StatesDesignCongressesDrugsSafety measuresPharmaceutical biotechnologyDrugsDesign615/.10289Robinson Sally620917Pool Robert288454Giffin Robert B1653478Institute of Medicine (U.S.).Forum on Drug Discovery, Development, and Translation.MiAaPQMiAaPQMiAaPQBOOK9910809901503321Emerging safety science4004809UNINA