03333oam 2200745 a 450 991080917290332120240516071030.0978661320346597812832034631283203464978111997017011199701729780470659359047065935197804706567920470656794(CKB)3460000000000125(EBL)711788(OCoLC)711780324(SSID)ssj0000541431(PQKBManifestationID)12181599(PQKBTitleCode)TC0000541431(PQKBWorkID)10499052(PQKB)10412482(MiAaPQ)EBC711788(Au-PeEL)EBL711788(CaPaEBR)ebr10484890(CaONFJC)MIL320346(PPN)243368658(OCoLC)694600439(FINmELB)ELB178568(Perlego)1013734(EXLCZ)99346000000000012520101221d2011 uy 0engur|n|---|||||txtccrSolid state characterization of pharmaceuticals /editors, Richard A. Storey, Ingvar Ymén1st ed.Chichester, U.K. John Wiley & Sons20111 online resource (528 pages)Description based upon print version of record.9781405134941 1405134941 Includes bibliographical references and index.Introduction to the solid state : physical properties and processes -- X-ray diffraction -- Spectroscopic characterisation -- Dielectric spectroscopy and thermally stimulated current spectroscopy : use in the characterisation of solid state pharmaceutical systems -- Solid state characterisation of pharmaceuticals -- Calorimetric methods : solution calorimetry -- Vapour sorption for bulk and surface analysis -- Microscopy -- Mechanical properties of pharmaceutical materials -- Particle size assessment -- Computational polymorph prediction -- Patenting of inventions relating to polymorphs -- A 'roadmap' to solid form selection.The field of solid state characterization is central to the pharmaceutical industry, as drug products are, in an overwhelming number of cases, produced as solid materials. Selection of the optimum solid form is a critical aspect of the development of pharmaceutical compounds, due to their ability to exist in more than one form or crystal structure (polymorphism). These polymorphs exhibit different physical properties which can affect their biopharmaceutical properties. This book provides an up-to-date review of the current techniques used to characterize pharmaceutical solids. Ensuring balanSolid dosage formsDrugsDesignPharmaceutical chemistrySolid dosage forms.DrugsDesign.Pharmaceutical chemistry.615/.19Storey Richard A109522Ymen Ingvar1654866MiAaPQMiAaPQMiAaPQBOOK9910809172903321Solid state characterization of pharmaceuticals4006968UNINA