03638nam 2200553 a 450 991080820750332120230725023411.01-282-54804-297866125480480-470-66037-60-470-66038-4(CKB)2670000000016995(EBL)514465(OCoLC)612432607(SSID)ssj0000413544(PQKBManifestationID)11913183(PQKBTitleCode)TC0000413544(PQKBWorkID)10399354(PQKB)11570014(MiAaPQ)EBC514465(Au-PeEL)EBL514465(CaPaEBR)ebr10380981(CaONFJC)MIL254804(EXLCZ)99267000000001699520091230d2010 uy 0engur|n|---|||||txtccrCardiotoxicity of non-cardiovascular drugs[electronic resource] /editor, Giorgio MinottiChichester, West Sussex Wiley20101 online resource (362 p.)Description based upon print version of record.0-470-77274-3 Includes bibliographical references and index.Machine generated contents note: List of Contributors -- 1. Mitochondrial Dysfunction In Cell Injury and Cardiotoxicity -- Fabio Di Lisa, Martina Semenzato, Andrea Carpi, Sara Menazza, Nina Kaludercic, Roberta Menabò, Marcella Canton -- 2. Cardiovascular Liabilities of Drugs: Regulatory Aspects -- Claudio Arrigoni -- 3. Cellular Mechanisms, Molecular Targets, and Structure-Function Relationships In Drug-Induced Arrhythmias: The Case Of Antihistamines, Psychoactive Drugs, and Antimicrobial Agents -- Maria Virginia Soldovieri and Maurizio Taglialatela -- 4. Cardiovascular Toxicity of Antitumor Drugs: Dimensions of the Problem in Children -- Rebecca Scully, Louis Pruitt, Steven E. Lipshultz -- 5. Cardiovascular Toxicity of Antitumor Drugs: Dimension of the Problem in Adult Settings -- Joseph R. Carver and Chaitali J. Desai -- 6. Diagnostic Aspects of Cardiovascular Toxicity of Antitumor Drugs -- Michael S. Ewer, Thomas M. Suter -- 7. Cardiovascular Toxicity of Antitumor Drugs: Translating Molecular Mechanisms into Clinical Facts -- Pierantonio Menna, Emanuela Salvatorelli, Carlo Salsano, Luca Gianni*, and Giorgio Minotti -- 8. NSAID Action and the Foundations for Cardiovascular Toxicity -- Anna L. Blobaum and Lawrence J. Marnett -- 9. Cardiovascular toxicities of NSAIDS: Epidemiologic aspects -- Antonio González-Pe;rez, Luis Alberto Garci;a Rodriguez -- 10. Cardiovascular Toxicities of Life-Saving Drugs: Antiviral Therapy -- James J. Kohler & William Lewis."First book to deal with this important area of adverse drug reactions -- cardiotoxicity is one of the major forms of toxicity seen in drugs and it accounts for most drug recalls and delays experienced in regulatory approvals. Covers four important therapeutic classes: psychoactive drugs; anticancer drugs; non-steroidal anti-inflammatory drugs; and anti-retroviral drugs. - Emphasis on the preclinical screening of drug cardiotoxicity, to enable drug developers to test for this toxicity before starting expensive clinical trials"--Provided by publisher.Cardiovascular toxicologyCardiovascular toxicology.616.1/061Minotti Giorgio1625934MiAaPQMiAaPQMiAaPQBOOK9910808207503321Cardiotoxicity of non-cardiovascular drugs3961712UNINA