04595nam 2200601Ia 450 991080787830332120240410164702.01-61942-869-5(CKB)2550000001040691(EBL)3017873(SSID)ssj0000918868(PQKBManifestationID)12343231(PQKBTitleCode)TC0000918868(PQKBWorkID)10908813(PQKB)11540774(MiAaPQ)EBC3017873(Au-PeEL)EBL3017873(CaPaEBR)ebr10654844(OCoLC)923654006(EXLCZ)99255000000104069120111102d2012 uy 0engur|n|---|||||txtccrAtaxia[electronic resource] causes, symptoms and treatment /Sung Hoi Hong, editor1st ed.New York Nova Science Publishersc20121 online resource (213 p.)Neuroscience research progressDescription based upon print version of record.1-61942-867-9 Includes bibliographical references and index.""ATAXIA ""; ""ATAXIA ""; ""CONTENTS ""; ""PREFACE ""; ""ROLE OF THE ATAXIA TELANGIECTASIA MUTATED PROTEIN IN STRESS-INDUCED PREMATURE SENESCENCE ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""ATM ACTIVATION ""; ""ATM SUBSTRATES ""; ""P53 STRUCTURE, ACTIVATION AND FUNCTION ""; ""ROLES OF ATM AND P53 IN DNA REPAIR""; ""MULTIPLE FUNCTIONS OF P21 IN THE ATM NETWORK ""; ""SEQUENTIAL WAVES OF P53 ACTIVATION BY DNA DAMAGE ""; ""ATM-DEPENDENT SENESCENCE ""; ""ATM-INDEPENDENT SENESCENCE ""; ""ROLE OF ATM IN PREVENTING ESCAPE FROM SIPS: A NOVEL TUMOR SUPPRESSOR FUNCTION BEYOND P53? """"POTENTIAL THERAPEUTIC APPROACHES FOR THE TREATMENT OF AT """"CONCLUSION""; ""ACKNOWLEDGMENTS ""; ""REFERENCES""; ""ATAXIA TELANGIECTASIA: MOLECULAR BASIS, DIAGNOSIS AND TREATMENT ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""CLINICAL FEATURES OF A-T ""; ""Neurological Phenotype and Cutaneous Manifestations ""; ""Immunodeficiency and Pulmonary Complications ""; ""Predisposition to Cancer and Chromosomal Instability""; ""Endocrine Dysfunction ""; ""PATHOGENESIS AND MOLECULAR DEFECT ""; ""ATM and Neurodegeneration""; ""ATM and Oxidative Stress ""; ""DIAGNOSIS AND TREATMENT ""; ""CONCLUSION """"REFERENCES """"THE NEUROBIOLOGY OF EPISODIC ATAXIA TYPE 1, A SHAKER-LIKE K+ CHANNEL DISORDER ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""STRUCTURE AND FUNCTION OF SHAKER-LIKE K+ CHANNELS ""; ""PHYSIOLOGICAL ROLE OF KV CHANNELS ""; ""Hippocampus ""; ""Cerebellum ""; ""Sciatic Nerve ""; ""BIOTECHNOLOGY FOR STUDYING ION CHANNELS ""; ""EPISODIC ATAXIA TYPE 1: ""; ""Clinical Findings ""; ""Genetic Causes ""; ""Molecular Pathogenetic Mechanisms Underlying EA1""; ""Animal Models of EA1""; ""Treatment of EA1 ""; ""BRIEF OVERVIEW OF RELATED ATAXIA DISORDERS ""; ""CONCLUSION ""; ""ACKNOWLEDGMENTS """"REFERENCES """"MITOCHONDRIAL ATAXIAS ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""ATAXIA IN MITOCHONDRIAL DISORDERS ""; ""MtDNA Point Mutations ""; ""MtDNA Sporadic Rearrangements ""; ""Infantile Onset Spinocerebellar Ataxia ""; ""POLG1-Related Diseases ""; ""OPA1-Related Diseases ""; ""Coenzyme Q10 Deficiency ""; ""FRIEDREICH ATAXIA ""; ""Mitochondrial Therapies for Friedreich Ataxia ""; ""MITOCHONDRIA AND OTHER GENETIC ATAXIAS ""; ""Dominant Spino-Cerebellar Ataxias ""; ""X-Linked Ataxias ""; ""CONCLUSION ""; ""REFERENCES """"EPIDEMIC SEASONAL ATAXIC SYNDROME: EPIDEMIOLOGY, CLINICAL PRESENTATION, ETIOLOGICAL MECHANISMS AND THERAPY """"ABSTRACT ""; ""INTRODUCTION ""; ""ETIOLOGY ""; ""Viral Hypothesis ""; ""Toxins in Food""; ""Hypothesis of Thiamine Deficiency ""; ""CLINICAL PRESENTATION OF SAS IS COMPATIBLE WITH WERNICKE�S ENCEPHALOPATHY ""; ""MECHANISM OF THIAMINE DEFICIENCY IN SEASONAL ATAXIC SYNDROME ""; ""THERAPY AND CONTROL OF SAS ""; ""REFERENCES ""; ""CLINICAL AND GENETIC ASPECTS OF RECESSIVE ATAXIAS ""; ""ABSTRACT ""; ""INTRODUCTION ""; ""THE DEGENERATIVE ATAXIAS ""; ""Friedreich�s Ataxia """"Autosomal Recessive Spastic Ataxia of Charlevoix-Saguenay (ARSACS) ""Neuroscience Research ProgressAtaxiaMovement disordersAtaxia.Movement disorders.Hong Sung Hoi1687065MiAaPQMiAaPQMiAaPQBOOK9910807878303321Ataxia4060262UNINA